FOLLOW UP BIOPSY AFTER CHEMORADIATION
CLINICAL NOTES: Peri-anal skin Bx - 3 o'clock. Subcutaneous anal tissue - 3 o'clock. 60 y/o F with PHx anal adenoCa treated with chemo + XRT for rebiopsy.
MACROSCOPIC DESCRIPTION:
1. "Perianal skin 3 o'clock": A polypoid fragment of tan tissue 10mm. Bisected. A1.
2. "Subcutaneous tissue 3 o'clock": A fragment of fibrous tissue 8mm. A1.
MICROSCOPIC DESCRIPTION:
1. Sections show squamous mucosa with normal maturation. The lamina propria is moderately fibrotic with a chronic inflammatory infiltrate and occasional dilated vessels. There is no evidence of dysplasia or an invasive malignancy.
2. Sections show fibrous and fatty tissue with a small amount of squamous epithelium. There is no evidence of dyplasia or of an invasive malignancy.
DIAGNOSIS:
1. Perianal skin, 3 o'clock: Benign squamous mucosa.
2. Subcutaneous tissue 3 o'clock: Benign fibrofatty tissue