Glioblastoma NOS (multicentric)

Discussion:

Histopathology of the largest lesion revealed WHO grade IV glioblastoma with pleomorphic astrocytes and marked atypia and mitotic figures. The frontal lesion does not appear to be connected to the occipital lesions by abnormal T2 signal, and thus the term multicentric glioblastoma would be favored over multifocal. 

Note: IDH mutation status is not provided in this case and according to the current (2016) WHO classification of CNS tumors, this tumor would, therefore, be designated as a glioblastoma NOS

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