Acute cerebral infarct complicated by history of prothrombin mutation

Discussion:

CT brain shows findings suggestive of ischemia in the right middle cerebral artery territory and this is confirmed on MRI images above.

This patient was admitted under the Neurology team and recovered with no significant residual deficits. A full stroke work up during admission found no evidence of a haemodynamically significant stenosis on carotid doppler ultrasound and no overt evidence of cardioembolic source was found on a transoesphageal echocardiogram. Nil specific intervention was instituted. Hematology discussed options for consideration of lifelong anticoagulation in the context of her prothrombin genetic mutation but this was not deemed appropriate. She was advised to continue with daily, low dose aspirin.

A repeat CT brain three weeks following initial imaging showed evidence of evolving gliosis at the sites of infarction but no further progression of the region of hemorrhagic transformation.

 

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