Terminal ileum carcinoid - well differentiated neuroendocrine tumour (pathology)
Diagnosis certain
Presentation
Presents with obstructive symptoms. The patient underwent a right hemicolectomy.
Patient Data
Age: 60 years
Gender: Female
Hemicolectomy.
{"current_user":null,"step_through_annotations":true,"access":{"can_edit":false,"can_download":true,"can_toggle_annotations":true,"can_feature":false,"can_examine_pipeline_reports":false,"can_pin":false},"extraPropsURL":"/studies/15987/annotated_viewer_json?lang=gb"}
Macroscopic:
- right hemicolectomy photograph includes segment of terminal ileum, caecum and ascending colon with tumour just visible in the distal terminal ileum
- the tumour is
- 18 mm in diameter
- mucosally based
- pale, homogeneous
- shows extension into subserosal tissue (Nb the muscularis propria is invaded rather than destroyed and is seen as a 'C' shaped band of tissue within the tumour nodule)
Histology:
- the tumour forms variably sized, well circumscribed nests ('insular' pattern)
- high power shows
- uniform cells
- rounded nuclei
- granular chromatin (so-called 'salt and pepper' chromatin).
Case Discussion
This is good example of a terminal ileal carcinoid, now more commonly referred to as well differentiated neuroendocrine tumour. This lesion was staged as pT3 N1 (with lymph node metastases in 4 of 11 local lymph nodes.
Unable to process the form. Check for errors and try again.