Pathology proven hepatic adenoma.
Hepatic adenomas are benign epithelial neoplasm:
- most commonly solitary (multiplicity may suggest hepatic adenomatosis)
- richly vascular tumor which frequently contains hemorrhage and necrosis
- pseudocapsule derived from compressed/collapsed hepatic parenchyma
- histological hallmark are clusters of benign hepatocytes arranged in sheets or cords with absent bile ducts
- Adenomas have variable lipid content ranging from
- microscopic fat (detected in up to 77% with chemical shift MR) to
- macroscopic fat (detected at CT in up 7%)
90% of hepatic adenomas occur in women. Associations with
- oral contraceptive use
- anabolic steroids
- glycogen storage disease (Type 1a)