Given the patient's history of aggressive malignancy, the finding on the initial chest radiograph is suspicious and warrants further evaluation by CT imaging. 

The finding of bulk fat within a pulmonary nodule is consistent with a benign etiology, most commonly pulmonary hamartoma or lipoid pneumonia. No follow-up was recommended for this lesion.

A repeat chest CT performed one year later for different reasons shows no interval change in the lesion, again consistent with benign hamartoma.