Subacute sclerosing panencephalitis

Discussion:

There are confluent areas of altered signal intensity in bilateral periventricular and subcortical white matter as described with associated mild volume loss.

These are non-specific findings and may be seen in certain metabolic disorders and leucoencephalopathies, and require correlation with clinical and laboratory findings.

In the given clinical scenario, the possibility of subacute sclerosing panencephalitis seems likely.

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