Pathology Report
FINAL DIAGNOSIS:
NODULE, LIVER, ULTRASOUND-GUIDED CORE BIOPSY:
1. LIVER CELL ADENOMA (SEE COMMENT).
2. NO EVIDENCE OF METASTATIC CARCINOMA.
COMMENT: The morphologic and immunohistochemical findings are most consistent with liver cell adenoma. If multiple, the diagnosis "liver cell adenomatosis" has been used.
CLINICAL HISTORY: Multiple liver nodules; long history of oral contraceptive use
PREOPERATIVE DIAGNOSIS: Same
POSTOPERATIVE DIAGNOSIS: Same
SPECIMEN(S): Liver mass
GROSS DESCRIPTION:
Received in formalin labeled with the patient's name and "liver biopsy" and consists of five red-tan, needle-core fragments ranging from 0.2 x 0.1 x 0.1 cm to the largest of 2.0 cm in length with a diameter of 0.1 cm. The specimen is submitted entirely within two mesh cassettes. Due to the minute size of the smallest fragment, it may not survive processing.
MICROSCOPIC DESCRIPTION:
A microscopic examination has been performed and the findings incorporated into the diagnosis. Immunohistochemical/special stain(s) is/are performed on block(s) A1 and A2.
Medical necessity for performing stain(s): To enable diagnosis
The stain(s) is/are evaluated following validation of appropriate control reactivity, with the following result(s):
STAIN/RESULT
Reticulin Highlights hepatic architecture consistent with adenoma
CD31 Highlights vascularity
CD34 "Complete" staining pattern
Beta catenin Uniform membranous staining