Langerhans cell histiocytosis is a rare, multi-systemic pathology that can affect many organs, including bones and lungs and largely affecting females, with a higher prevalence in smokers.

In the present case, the symptomatology began at a skeletal level, but showing some pulmonary findings compatible with an early stage of pulmonary involvement.

The diagnosis was made with the biopsy of a spinal lesion, with histology confirming Langerhans cell histiocytosis