Rathke's cleft cyst

Discussion:

The patient went on to have a transsphenoidal resection. 

Histology

The sections show a small fragment of tissue which is covered on one surface by a layer of ciliated cuboidal epithelial cells. These show strong immunostaining for cytokeratins CAM5.2 and AE1/AE3. The underlying tissue contains a moderate chronic inflammatory cell infiltrate. No anterior pituitary acini are identified. The features are consistent with the wall and lining of a Rathke's cleft cyst. No evidence of tumor is seen.

FINAL DIAGNOSIS: Features consistent with wall and lining of Rathke's cleft cyst.

 

The patient has been followed up for 7 years and is doing well without recurrence. 

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