Histopathology
MACROSCOPIC DESCRIPTION: "Right distal radius biopsy": Three cream and haemorrhagic tissue cores with a total length of 40mm.
MICROSCOPIC DESCRIPTION: Sections show fibrocollagenous tissue cores containing a moderately cellular tumour composed of abundant multinucleated giant cells and mononuclear cells. Tumour cells contain amphophilic to foamy cytoplasm. Occasional cells contain brown haemosiderin pigment. No necrosis, atypia or mitoses are seen. The histological features are those of a giant cell tumour of bone. Clinical and radiological correlation is recommended.
DIAGNOSIS: Right distal radius biopsy: Giant cell tumour of bone.