How to describe the eccentric target sign (cerebral toxoplasmosis)?
It is seen on postcontrast MRI/CT as a ring-enhancing lesion with an eccentrically located enhancing mural nodule.
What is the histopathological of eccentric target sign(cerebral toxoplasmosis)?
The central enhancing core of the target seen on MRI was produced by a leash of inflamed vessels extending down the length of the sulcus that was surrounded by concentric zones of necrosis and a wall composed of histiocytes and proliferating blood vessels, with impaired permeability producing the peripheral enhancing rim.[1]
What is the specificity and sensitivity of an eccentric target sign in the diagnosis of cerebral toxoplasmosis?
95% specificity and 25% sensitivity [1]
The lesion in the corticomedullary junction of the right frontal reveals a ring-enhancing with eccentric target sign on T1C+ (yellow arrow).