Renal/perirenal lymphoma

Discussion:

Patient with several year history of lymphoma on and off chemotherapy. Fairly characteristic appearance of renal/perirenal disease with multiple ill defined masses and involvement of the cortex. 

Given moderate hydronephrosis, urology consult would be appropriate. If tissue diagnosis were needed, ultrasound-guided biopsy would be feasible. 

The differential diagnosis for perirenal infiltrative soft tissue involves several unusual diagnoses, and is worth trying to remember: 

  • lymphoma
  • retroperitoneal fibrosis
  • igG4 sclerosing disease
  • Erdheim-Chester disease
  • extramedullary hematopoiesis
  • amyloidosis
  • plasmacytoma
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