Lumbar spine ependymoma (WHO grade 2)

Discussion:

Biopsy result

The sections show a moderately cellular tumor, forming perivascular pseudorosettes. The tumor cells form cuffs around blood vessels. The tumor cells have mildly enlarged round to ovoid nuclei and small nucleoli. There is no myxoid material in the background. Mitoses are inconspicuous. There is no microvascular proliferation or necrosis. The tumor cells are diffusely GFAP positive. There is focal EMA positivity with perinuclear dot-like pattern. The Ki-67 index is up to about 3%. The features are those of ependymoma.

DIAGNOSIS: Lumbar spinal tumor: Ependymoma (WHO Grade II).

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