An old adult presenting with the first episode of seizure were assessed by a CT scan (not available) that depicted the cerebral lesion better evaluated on MRI, with typical features of a high-grade glioma. 

Surgery resection confirmed the diagnosis of a glioblastoma, specifically a wild-type, based on its immunohistochemistry. 

• IDH-1 negative (not mutated) = 'wild type' = poor prognosis
• ATRX Positive (not mutated) 
• MGMT Negative (likely methylated)