Adenosquamous carcinoma of lung
Updates to Article Attributes
Adenosquamous carcinoma (ASC) of the lung is a rare type of non-small cell lung cancer containing both components of lung adenocarcinoma and lung squamous cell carcinoma (SCC).
Epidemiology
It is thought to constituting 0.4-4% of cases non-small cell lung cancer.
Risk factors
- cigarette smoking 8
Pathology
The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and squamous cell carcinoma, with each comprising at least 10% of the tumour 4.
Location
There may be a slight predominance towards the periphery of the lung 5-6.
Radiographic features
General
There appears to be a wide imaging spectrum both in terms of size and morphology 5. Differentiation from other histological forms on imaging grounds alone can be difficult, if not impossible. They usually present as a single lesion, with mean tumour size ranging from 2.8 to 3.8 cm (range 0.6-11 cm), based on two studies 5-6.
Treatment and prognosis
It is thought to be more aggressive than both pure adenocarcinomaadenocarcinomas of the lung and pure squamous cell carcinomacarcinomas of the lung 1. Early stageThe early-stage disease may be amenable to surgery. There may also be an increased rate of lymph node metastases at the time of presentation compared with other histological types 7.
-<p><strong>Adenosquamous carcinoma (ASC) of the lung</strong> is a rare type of <a href="/articles/non-small-cell-lung-cancer-2">non-small cell lung cancer</a>.</p><h4>Epidemiology</h4><p>It is thought to constituting 0.4-4% of cases non-small cell lung cancer.</p><h5>Risk factors</h5><ul><li>cigarette smoking <sup>8</sup>-</li></ul><h4>Pathology</h4><p>The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and squamous cell carcinoma, with each comprising at least 10% of the tumour <sup>4</sup>.</p><h5>Location</h5><p>There may be a slight predominance towards the periphery of the lung <sup>5-6</sup>.</p><h4>Radiographic features</h4><h5>General</h5><p>There appears to be a wide imaging spectrum both in terms of size and morphology <sup>5</sup>. Differentiation from other histological forms on imaging grounds alone can be difficult. They usually present as a single lesion, with mean tumour size ranging from 2.8 to 3.8 cm (range 0.6-11 cm), based on two studies <sup>5-6</sup>.</p><h4>Treatment and prognosis</h4><p>It is thought to be more aggressive than both pure <a href="/articles/adenocarcinoma-of-the-lung">adenocarcinoma of the lung</a> and pure <a href="/articles/squamous-cell-carcinoma-of-the-lung">squamous cell carcinoma of the lung</a> <sup>1</sup>. Early stage disease may be amenable to surgery. There may also be an increased rate of lymph node metastases at the time of presentation compared with other histological types <sup>7</sup>. </p>- +<p><strong>Adenosquamous carcinoma of the lung</strong> is a rare type of <a href="/articles/non-small-cell-lung-cancer-3">non-small cell lung cancer</a> containing both components of <a title="Lung adenocarcinoma" href="/articles/adenocarcinoma-of-the-lung">lung adenocarcinoma</a> and <a title="Squamous cell carcinoma of lung" href="/articles/squamous-cell-carcinoma-of-the-lung">lung squamous cell carcinoma (SCC)</a>. </p><h4>Epidemiology</h4><p>It is thought to constituting 0.4-4% of cases non-small cell lung cancer.</p><h5>Risk factors</h5><ul><li>cigarette smoking <sup>8</sup>
- +</li></ul><h4>Pathology</h4><p>The definition of adenosquamous carcinoma indicates a carcinoma showing components of adenocarcinoma and squamous cell carcinoma, with each comprising at least 10% of the tumour <sup>4</sup>.</p><h5>Location</h5><p>There may be a slight predominance towards the periphery of the lung <sup>5-6</sup>.</p><h4>Radiographic features</h4><h5>General</h5><p>There appears to be a wide imaging spectrum both in terms of size and morphology <sup>5</sup>. Differentiation from other histological forms on imaging grounds alone can be difficult, if not impossible. They usually present as a single lesion, with mean tumour size ranging from 2.8 to 3.8 cm (range 0.6-11 cm), based on two studies <sup>5-6</sup>.</p><h4>Treatment and prognosis</h4><p>It is thought to be more aggressive than both pure <a href="/articles/adenocarcinoma-of-the-lung">adenocarcinomas of the lung</a> and pure <a href="/articles/squamous-cell-carcinoma-of-the-lung">squamous cell carcinomas of the lung</a> <sup>1</sup>. The early-stage disease may be amenable to surgery. There may also be an increased rate of lymph node metastases at the time of presentation compared with other histological types <sup>7</sup>. </p>
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