Apple core sign (colon)

Changed by Frank Gaillard, 12 Nov 2019

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The apple core sign, also known as the napkin ring sign (bowel), is most frequently associated with constriction of the lumen of the colon by a stenosing annular colorectal carcinoma.

Differential diagnosis

The appearance of the apple-core lesion of the colon also can be caused by other diseases ³:

lymphoma with colonic involvement - appears more diffuse
Crohn disease
chronic ulcerative colitis
ischaemic colitis
chlamydia infection
colonic tuberculosis
helminthoma
colonic amoebiasis
colonic cytomegalovirus
villous adenoma
radiosurgery e.g. high dose CyberKnife used for treating unresectable abdominal malignancies

~~-<a title="Colonic lymphomas" href="/articles/large-bowel-lymphoma">lymphoma with colonic involvement</a> - appears more diffuse</li>~~
+<a href="/articles/large-bowel-lymphoma">lymphoma with colonic involvement</a> - appears more diffuse</li>
~~-<li>~~
~~-<a title="Ulcerative colitis" href="/articles/ulcerative-colitis">chronic </a><a href="/articles/ulcerative-colitis">ulcerative colitis</a>~~
~~-</li>~~
+<li><a title="Ulcerative colitis" href="/articles/ulcerative-colitis">chronic ulcerative colitis</a></li>
~~-<li>helminthoma</li>~~
~~-<li><a title="Amoebiasis" href="/articles/amoebic-colitis">colonic amoebiasis</a></li>~~
~~-<li><a title="Gastrointestinal cytomegalovirus infection" href="/articles/gastrointestinal-cytomegalovirus-infection">colonic cytomegalovirus</a></li>~~
~~-<li><a title="Colorectal villous polyps" href="/articles/colorectal-villous-polyps">villous adenoma</a></li>~~
+<li><a title="helminthoma" href="/articles/helminthoma">helminthoma</a></li>
+<li><a href="/articles/amoebic-colitis">colonic amoebiasis</a></li>
+<li><a href="/articles/gastrointestinal-cytomegalovirus-infection">colonic cytomegalovirus</a></li>
+<li><a href="/articles/colorectal-villous-polyps">villous adenoma</a></li>
-<a title="Stereotactic radiosurgery" href="/articles/stereotactic-radiosurgery">radiosurgery</a> e.g. high dose <a title="CyberKnife" href="/articles/cyberknife-1">CyberKnife</a> used for treating unresectable abdominal malignancies</li>
+<a href="/articles/stereotactic-radiosurgery">radiosurgery</a> e.g. high dose <a href="/articles/cyberknife-1">CyberKnife</a> used for treating unresectable abdominal malignancies</li>

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Apple core sign (colon)

Updates to Article Attributes

Differential diagnosis

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