Cesarean scar ectopic pregnancy

Changed by Andrew Murphy, 5 Sep 2016

Updates to Article Attributes

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Caesarean scar ectopic pregnancy (CSEP) is a rare type of abnormal implantation. It is often considered the rarest type of ectopic pregnancy, although some do not includedinclude it in this category as implantation occurs within the uterus.

Epidemiology

It has an estimated incidence of ~1:1800-2200 pregnancies 2,3.  The overall incidence is however thought to be increasing 4, representing up to 6% of ectopic pregnancies in patients with a history of a Caesarean section 11.

Pathology

Poor healing can result in a focal thinning of the scar, which may be susceptible to implantation of the gestational sac at this point rather than in the endometrial cavity 10

Radiographic features

Ultrasound

Described sonographic features include:

  • empty uterus
  • empty cervical canal
  • development of the gestational sac in the anterior part of the lower uterine segment
  • an absence of myometrium between the bladder wall and the gestational sac

Treatment and prognosis

Ultrasound-guided methotrexate injection has emerged as the treatment of choice. Surgical or invasive techniques, including dilatation and curettage are not recommended due to high morbidity and poor prognosis. Because subsequent pregnancies may also be complicated by uterine rupture, the uterine scar should be evaluated before, as well as during the subsequent pregnancies.

Complications

Differential diagnosis

On ultrasound consider:

  • -<p><strong>Caesarean scar ectopic pregnancy (CSEP)</strong> is a rare type of abnormal implantation. It is often considered the rarest type of <a title="Ectopic pregnancy" href="/articles/ectopic-pregnancy">ectopic pregnancy</a>, although some do not included it in this category as implantation occurs within the uterus.</p><h4>Epidemiology</h4><p>It has an estimated incidence of ~1:1800-2200 pregnancies <sup>2,3</sup>.  The overall incidence is however thought to be increasing <sup>4</sup>, representing up to 6% of ectopic pregnancies in patients with a history of a Caesarean section <sup>11</sup>.</p><h4>Pathology</h4><p>Poor healing can result in a focal thinning of the scar, which may be susceptible to implantation of the <a href="/articles/gestational-sac">gestational sac</a> at this point rather than in the endometrial cavity <sup>10</sup>. </p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Described sonographic features include:</p><ul>
  • +<p><strong>Caesarean scar ectopic pregnancy (CSEP)</strong> is a rare type of abnormal implantation. It is often considered the rarest type of <a href="/articles/ectopic-pregnancy">ectopic pregnancy</a>, although some do not include it in this category as implantation occurs within the uterus.</p><h4>Epidemiology</h4><p>It has an estimated incidence of ~1:1800-2200 pregnancies <sup>2,3</sup>.  The overall incidence is however thought to be increasing <sup>4</sup>, representing up to 6% of ectopic pregnancies in patients with a history of a Caesarean section <sup>11</sup>.</p><h4>Pathology</h4><p>Poor healing can result in a focal thinning of the scar, which may be susceptible to implantation of the <a href="/articles/gestational-sac">gestational sac</a> at this point rather than in the endometrial cavity <sup>10</sup>. </p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Described sonographic features include:</p><ul>

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