Calcification of the globe (differential)

Changed by Craig Hacking, 13 Oct 2017

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Calcification of the globe has many causes, varying from the benign to malignant. When calcification is seen of the posterior half of the globe, it could relate to any of the layers (scleral, choroidal or retinal), as it is not possible to separate them out on CT.

Sclerochoroidal

metastatic calcification: abnormal calcium and phosphate metabolism
dystrophic calcification: abnormal tissues become calcified, despite normal calcium and phosphate metabolism, occasionally seen in elderly Caucasians, most frequently men
phthisis bulbi: is the end result of major injury to the eye (trauma, infection) with a shrunken calcified 'lump' remaining
scleral calcific plaques (senile)

Differential diagnosis

For globe opacification consider:

intraocular silicone gel treatment ⁴

-<p><strong>Calcification of the globe</strong> has many causes, varying from the benign to malignant. When calcification is seen of the posterior half of the globe, it could relate to any of the layers (scleral, choroidal or retinal), as it is not possible to separate them out on CT.</p><h5>Retinal</h5><ul>
+<p><strong>Calcification of the globe</strong> has many causes, varying from the benign to malignant. When calcification is seen of the posterior half of the <a title="Globe" href="/articles/globe-1">globe</a>, it could relate to any of the layers (scleral, choroidal or retinal), as it is not possible to separate them out on CT.</p><h5>Retinal</h5><ul>

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