Chronic osteomyelitis
Updates to Article Attributes
Body
was changed:
Chronic osteomyelitis is a form of osteomyelitis and is defined as a progressive inflammatory process resulting in bone destruction and sequestrum formation. It may present as recurrent or intermittent disease.
Pathology
It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years.
Radiographic features
Plain radiograph
Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.
CT
CT may provide information regarding the presence of sequestra, cloaca, cortical destruction and the thickness of the involucrum.
See also
-<p><strong>Chronic osteomyelitis </strong>is a form of <a href="/articles/osteomyelitis">osteomyelitis</a> and is defined as a progressive inflammatory process resulting in bone destruction and <a href="/articles/bony-sequestrum">sequestrum</a> formation. It may present as recurrent or intermittent disease.</p><h4>Pathology</h4><p>It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.</p><h5>CT</h5><p>CT may provide information regarding the presence of <a title="Bony sequestrum" href="/articles/bony-sequestrum">sequestra</a>, <a title="Cloaca (osteomyelitis)" href="/articles/cloaca-osteomyelitis-1">cloaca</a>, cortical destruction and the thickness of the <a title="Involucrum" href="/articles/involucrum">involucrum</a>.</p><h4>See also</h4><ul>- +<p><strong>Chronic osteomyelitis </strong>is a form of <a href="/articles/osteomyelitis">osteomyelitis</a> and is defined as a progressive inflammatory process resulting in bone destruction and <a href="/articles/bony-sequestrum">sequestrum</a> formation. It may present as recurrent or intermittent disease.</p><h4>Pathology</h4><p>It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.</p><h5>CT</h5><p>CT may provide information regarding the presence of <a href="/articles/bony-sequestrum">sequestra</a>, <a href="/articles/cloaca-osteomyelitis-1">cloaca</a>, cortical destruction and the thickness of the <a href="/articles/involucrum">involucrum</a>.</p><h4>See also</h4><ul>
References changed:
- 1. Panteli M & Giannoudis P. Chronic Osteomyelitis: What the Surgeon Needs to Know. EFORT Open Reviews. 2016;1(5):128-35. <a href="https://doi.org/10.1302/2058-5241.1.000017">doi:10.1302/2058-5241.1.000017</a>
- 2. Desimpel J, Posadzy M, Vanhoenacker F. The Many Faces of Osteomyelitis: A Pictorial Review. Journal of the Belgian Society of Radiology. 2017;101(1). <a href="https://doi.org/10.5334/jbr-btr.1300">doi:10.5334/jbr-btr.1300</a>
- 3. Pineda C, Espinosa R, Pena A. Radiographic Imaging in Osteomyelitis: The Role of Plain Radiography, Computed Tomography, Ultrasonography, Magnetic Resonance Imaging, and Scintigraphy. Semin Plast Surg. 2009;23(02):080-9. <a href="https://doi.org/10.1055/s-0029-1214160">doi:10.1055/s-0029-1214160</a>
- 4. Wing V, Jeffrey R, Federle M, Helms C, Trafton P. Chronic Osteomyelitis Examined by CT. Radiology. 1985;154(1):171-4. <a href="https://doi.org/10.1148/radiology.154.1.3964936">doi:10.1148/radiology.154.1.3964936</a>
- 1. Panteli M, Giannoudis PV. Chronic osteomyelitis: what the surgeon needs to know. (2016) EFORT open reviews. 1 (5): 128-135. <a href="https://doi.org/10.1302/2058-5241.1.000017">doi:10.1302/2058-5241.1.000017</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/28461939">Pubmed</a> <span class="ref_v4"></span>
- 2. Julie Desimpel, Magdalena Posadzy, Filip M. Vanhoenacker. The Many Faces of Osteomyelitis: A Pictorial Review. (2017) Journal of the Belgian Society of Radiology. 101 (1): 24. <a href="https://doi.org/10.5334/jbr-btr.1300">doi:10.5334/jbr-btr.1300</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/30039016">Pubmed</a> <span class="ref_v4"></span>
- 3. Pineda C, Espinosa R, Pena A. Radiographic imaging in osteomyelitis: the role of plain radiography, computed tomography, ultrasonography, magnetic resonance imaging, and scintigraphy. (2009) Seminars in plastic surgery. 23 (2): 80-9. <a href="https://doi.org/10.1055/s-0029-1214160">doi:10.1055/s-0029-1214160</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/20567730">Pubmed</a> <span class="ref_v4"></span>
- 4. Wing VW, Jeffrey RB, Federle MP, Helms CA, Trafton P. Chronic osteomyelitis examined by CT. (1985) Radiology. 154 (1): 171-4. <a href="https://doi.org/10.1148/radiology.154.1.3964936">doi:10.1148/radiology.154.1.3964936</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/3964936">Pubmed</a> <span class="ref_v4"></span>
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