Chronic osteomyelitis
Updates to Article Attributes
Chronic osteomyelitis is a form of osteomyelitis and is defined as a progressive inflammatory process resulting in bone destruction and sequestrum formation. Bacteria Bacteria and fungi can cause it. It It may present as recurrent or intermittent disease.
Pathology
It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years. It is characterised by increased inflammatory neutrophils, plasma cells, and and lymphocytes.
Radiographic features
Plain radiograph
Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.
CT
CT may provide information regarding the presence of sequestra, cloaca, cortical destruction and the thickness of the involucrum.
See also
-<p><strong>Chronic osteomyelitis </strong>is a form of <a href="/articles/osteomyelitis">osteomyelitis</a> and is defined as a progressive inflammatory process resulting in bone destruction and <a href="/articles/bony-sequestrum">sequestrum</a> formation. Bacteria and fungi can cause it. It may present as recurrent or intermittent disease.</p><h4>Pathology</h4><p>It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years. It is characterised by increased inflammatory neutrophils, plasma cells, and lymphocytes.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.</p><h5>CT</h5><p>CT may provide information regarding the presence of <a href="/articles/bony-sequestrum">sequestra</a>, <a href="/articles/cloaca-osteomyelitis-1">cloaca</a>, cortical destruction and the thickness of the <a href="/articles/involucrum">involucrum</a>.</p><h4>See also</h4><ul>- +<p><strong>Chronic osteomyelitis </strong>is a form of <a href="/articles/osteomyelitis">osteomyelitis</a> and is defined as a progressive inflammatory process resulting in bone destruction and <a href="/articles/bony-sequestrum">sequestrum</a> formation. Bacteria and fungi can cause it. It may present as recurrent or intermittent disease.</p><h4>Pathology</h4><p>It is a result of osteonecrosis caused by disruption of intraosseous and periosteal blood supply during the acute stage of the disease. A dead infected bone fragment becomes separated from viable bone (known as a sequestrum). Infective agents within the devascularised sequestrum become protected from antibiotics and the endogenous immune response, forming a nidus for chronic infection. This may persist for years. It is characterised by increased inflammatory neutrophils, plasma cells, and lymphocytes.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><p>Inhomogeneous osteosclerosis and/or sequestrum formation (necrotic bone) is characteristic of chronic osteomyelitis on plain radiography.</p><h5>CT</h5><p>CT may provide information regarding the presence of <a href="/articles/bony-sequestrum">sequestra</a>, <a href="/articles/cloaca-osteomyelitis-1">cloaca</a>, cortical destruction and the thickness of the <a href="/articles/involucrum">involucrum</a>.</p><h4>See also</h4><ul>
Image 12 X-ray (Lateral) ( destroy )
Image 12 MRI (T2) ( update )
Image 13 CT (non-contrast) ( update )
Image 14 MRI (PD fat sat) ( update )
Image 15 CT (bone window) ( update )
Image 16 MRI (PD fat sat) ( update )
Image 17 CT (bone window) ( update )
Image 18 X-ray (Frontal) ( update )
Image 19 X-ray (Frontal) ( update )
Unable to process the form. Check for errors and try again.