Congenital limb amputation is the absence of a fetal limb or part of a limb that usually occurs due to disruption of vascular supply.
Congenital amputations occur in 0.5 (range 0.03-1) per 1000 live births 2.
They are slightly more common in the upper limb (60%) than in the lower limb (40%) 2.
- amniotic band syndrome (most common 3)
- amniotic adhesion
- resorptive necrosis due to limb movement restriction in oligohydramnios
- vasoactive teratogens
- 1. Ferns, S; Sharma, R; Narayanan, P; Bhat, B.V. Limb Amputation Defects In Utero-A Case Report. J Anat. Soc. India 50(2) 156-158 (2001).
- 2. May BJ, Lockard MA. Prosthetics & Orthotics in Clinical Practice A Case Study Approach. F A Davis. ISBN:B00HYX3XEQ. Read it at Google Books - Find it at Amazon
- 3. Differential Diagnosis in Pediatric Radiology. Thieme Publishing Group. (1999) ISBN:3131081317. Read it at Google Books - Find it at Amazon