Diffuse hepatic steatosis (grading)

Changed by Ayush Goel, 30 Dec 2017

Updates to Article Attributes

Body was changed:

Grading of diffuse hepatic steatosis on ultrasound has been used to communicate to the clinician about the extent of fatty changes in the liver. 

Grading

  • grade I:diffusely increased hepatic echogenicity with visiblebut periportal and diaphragmatic echogenicity is still appreciable
  • grade II: increased diffusely increased hepatic echogenicity with imperceptibleobscuring periportal echogenicity, without obscuration of diaphragm but diaphragmatic echogenicity is still appreciable 
  • grade III: increased diffusely increased hepatic echogenicity with imperceptibleobscuring periportal as well as diaphragmatic echogenicity and obscuration of diaphragm

Practical points

Some suggest that visual grading of hepatic steatosis is subject to a wide interobserver and intraobserver variability 3

There is also a histological three point scale for grading severity of non-alcoholic steatohepatitis 4. These two grading systems are not currently correlated.

  • -<strong>grade I: </strong>increased hepatic echogenicity with visible periportal and diaphragmatic echogenicity</li>
  • +<strong>grade I: </strong>diffusely increased hepatic echogenicity but periportal and diaphragmatic echogenicity is still appreciable</li>
  • -<strong>grade II:</strong> increased hepatic echogenicity with imperceptible periportal echogenicity, without obscuration of diaphragm</li>
  • +<strong>grade II:</strong> diffusely increased hepatic echogenicity obscuring periportal echogenicity but diaphragmatic echogenicity is still appreciable </li>
  • -<strong>grade III:</strong> increased hepatic echogenicity with imperceptible periportal echogenicity and obscuration of diaphragm</li>
  • +<strong>grade III:</strong> diffusely increased hepatic echogenicity obscuring periportal as well as diaphragmatic echogenicity </li>

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