Diffuse peritoneal leiomyomatosis
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Diffuse/disseminated peritoneal leiomyomatosis (also(DPL),also known as leiomyomatosis peritonealis disseminata), is an exceedingly rare benign disorder characterised by multiple vascular leiomyomas growing along the submesothelial tissues of the abdomino-pelvic abdominopelvic peritoneum.
Epidemiology
ItDPL is usually discovered incidentally in women of reproductive age.
Pathology
Associations
- long-term use of oral contraceptives
- granulosa cell tumours of the ovary 1
- pregnancy 5
Radiographic features
General
A spectrum of features can be seen ranging from multiple solid subcentimetric nodules like those in peritoneal carcinomatosis to large solid masses on both ultrasoudnultrasound and CT. These masses may show homogeneous or heterogeneous attenuation with a variable enhancement pattern similar to that of uterine leiomyomas.
MRI
May show multiple masses with signal intensity similar to that of skeletal muscle and smooth muscle on both T1-T1WI and T2-weighted images and with homogeneousT2WI. Homogeneous enhancement following the administration of contrast material.
Etymology
The condition was first defined by H D Taubert et al in in 1965 3.
Differential diagnosis
General considerations include
-
peritoneal carcinomatosis: typically
haspatients have associatedweightweight loss, ascites, and disease progression observed at imaging.
See also
-<p><strong>Diffuse peritoneal leiomyomatosis</strong> (also known as <strong>leiomyomatosis peritonealis disseminata</strong>) is an exceedingly rare benign disorder characterised by multiple vascular <a href="/articles/parasitic-leiomyoma">leiomyomas</a> growing along the submesothelial tissues of the abdomino-pelvic peritoneum.</p><h4><strong>Epidemiology</strong></h4><p>It is usually discovered incidentally in women of reproductive age.</p><h4><strong>Pathology</strong></h4><h5><strong>Associations</strong></h5><ul>- +<p><strong>Diffuse/disseminated peritoneal leiomyomatosis </strong>(<strong>DPL</strong>),<strong> </strong>also known as <strong>leiomyomatosis peritonealis disseminata</strong>, is an exceedingly rare benign disorder characterised by multiple vascular <a href="/articles/parasitic-leiomyoma">leiomyomas</a> growing along the submesothelial tissues of the abdominopelvic <a href="/articles/peritoneum">peritoneum</a>.</p><h4>Epidemiology</h4><p>DPL is usually discovered incidentally in women of reproductive age.</p><h4>Pathology</h4><h5>Associations</h5><ul>
-<a href="/articles/granulosa-cell-tumour-of-ovary">granulosa cell tumours of the ovary</a> <sup>1</sup>- +<a href="/articles/granulosa-cell-tumour-of-the-ovary-1">granulosa cell tumours of the ovary</a> <sup>1</sup>
-</ul><h4><strong>Radiographic features</strong></h4><h5><strong>General</strong></h5><p>A spectrum of features can be seen ranging from multiple solid subcentimetric nodules like those in peritoneal carcinomatosis to large solid masses on both ultrasoudn and CT. These masses may show homogeneous or heterogeneous attenuation with a variable enhancement pattern similar to that of uterine leiomyomas.</p><h5><strong>MRI</strong></h5><p>May show multiple masses with signal intensity similar to that of skeletal muscle and smooth muscle on both T1- and T2-weighted images and with homogeneous enhancement following the administration of contrast material</p><h4><strong>Etymology</strong></h4><p>The condition was first defined by <strong>H D Taubert</strong> et al in 1965 <sup>3 </sup></p><h4><strong>Differential diagnosis</strong></h4><p>General considerations include</p><ul><li>-<a href="/articles/peritoneal-carcinomatosis">peritoneal carcinomatosis</a> : typically has associated weight loss, ascites, and disease progression observed at imaging.</li></ul><h4><strong>See also</strong></h4><ul>- +<li>pregnancy <sup>5</sup>
- +</li>
- +</ul><h4>Radiographic features</h4><p>A spectrum of features can be seen ranging from multiple solid subcentimetric nodules like those in peritoneal carcinomatosis to large solid masses on both ultrasound and CT. These masses may show homogeneous or heterogeneous attenuation with a variable enhancement pattern similar to that of uterine leiomyomas.</p><h5>MRI</h5><p>May show multiple masses with signal intensity similar to that of skeletal muscle and smooth muscle on both T1WI and T2WI. Homogeneous enhancement following the administration of contrast material.</p><h4>History and etymology</h4><p>The condition was first defined by <strong>H D Taubert</strong> et al in 1965 <sup>3</sup>.</p><h4>Differential diagnosis</h4><p>General considerations include</p><ul><li>
- +<a href="/articles/peritoneal-carcinomatosis">peritoneal carcinomatosis</a>: typically patients have associated weight loss, <a href="/articles/ascites">ascites</a>, and disease progression observed at imaging</li></ul><h4>See also</h4><ul>
References changed:
- 5. Clement PB, Young RH. Atlas of Gynecologic Surgical Pathology: Expert Consult: Online (Atlases in Diagnostic Surgical Pathology). Saunders. ISBN:B00GC3C45I. <a href="http://books.google.com/books?vid=ISBNB00GC3C45I">Read it at Google Books</a> - <a href="http://www.amazon.com/gp/product/B00GC3C45I">Find it at Amazon</a><span class="auto"></span>
Systems changed:
- Gastrointestinal
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