Duodenitis
Disclosures
- updated 15 Jul 2022:
Nothing to disclose
Updates to Article Attributes
Body
was changed:
Duodenitis is a term given to inflammation of the duodenum.
Pathology
Aetiology
Duodenitis can result from both intrinsic processes within the duodenum as well as from processes occurring outside the duodenum. It can occur from infective as well as non-infective inflammatory processes.
Non-infective inflammatory
-
secondary involvement from-
pancreatitis: considered most common1 cholecystitis
-
-
Crohn disease: duodenal involvement in 0.5-4% of casesprimary involvement: ulcer, stricturesecondary involvement: enteric fistula
-
duodenal ulcers: occur most frequently in the duodenal bulb AIDSpost-radiation therapy
Infective
Helicobacter pylori: this has shown a near-universal relationship (>90%) with duodenal ulcers, an association with duodenitis remains unproven
.
Non-infective inflammatory
secondary involvement from
pancreatitis: considered most common 1
-
Crohn disease: duodenal involvement in 0.5-4% of cases
primary involvement: ulcer, stricture
secondary involvement: enteric fistula
duodenal ulcers: occur most frequently in the duodenal bulb
post-radiation therapy
Others
alcohol
-
gastric hypersecretion
ectopic gastrinoma (Zollinger-Ellison syndrome)
Radiographic features
Findings include thickening of folds (if present, they are almost always found proximal to the ampulla of Vater), nodules or nodular folds, and erosions. Deformity of the duodenal bulb also may be seen.
Differential Diagnosisdiagnosis
Brunner
’sgland hyperplasia:isthe main consideration butis likelya rare disorder
-<p><strong>Duodenitis</strong> is a term given to inflammation of the <a href="/articles/duodenum">duodenum</a>.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Duodenitis can result from both intrinsic processes within the duodenum as well as from processes occurring outside the duodenum. It can occur from infective as well as non-infective inflammatory processes.</p><h6>Non-infective inflammatory</h6><ul>-<li>secondary involvement from<ul>- +<p><strong>Duodenitis</strong> is a term given to inflammation of the <a href="/articles/duodenum">duodenum</a>.</p><h4>Pathology</h4><h5>Aetiology</h5><p>Duodenitis can result from both intrinsic processes within the duodenum as well as from processes occurring outside the duodenum. It can occur from infective as well as non-infective inflammatory processes.</p><h6>Infective</h6><ul>
- +<li><p><em>Helicobacter pylori</em>: this has shown a near-universal relationship (>90%) with duodenal ulcers, an association with duodenitis remains unproven</p></li>
- +<li><p><a href="/articles/giardiasis">giardiasis</a></p></li>
- +<li><p><a href="/articles/tropical-sprue">tropical sprue</a></p></li>
- +</ul><h6>Non-infective inflammatory</h6><ul>
-<a href="/articles/acute-pancreatitis">pancreatitis</a>: considered most common <sup>1</sup>-</li>-<li><a href="/articles/cholecystitis">cholecystitis</a></li>- +<p>secondary involvement from</p>
- +<ul>
- +<li><p><a href="/articles/acute-pancreatitis">pancreatitis</a>: considered most common <sup>1</sup></p></li>
- +<li><p><a href="/articles/cholecystitis">cholecystitis</a></p></li>
-<a href="/articles/crohn-disease-1">Crohn disease</a>: duodenal involvement in 0.5-4% of cases<ul>-<li>primary involvement: ulcer, stricture</li>-<li>secondary involvement: enteric fistula</li>- +<p><a href="/articles/crohn-disease-1">Crohn disease</a>: duodenal involvement in 0.5-4% of cases</p>
- +<ul>
- +<li><p>primary involvement: ulcer, <a href="/articles/colonic-stricture" title="Colonic stricture">stricture</a></p></li>
- +<li><p>secondary involvement: <a href="/articles/enteroenteric-fistula" title="Enteroenteric fistula">enteric fistula</a></p></li>
-<li>-<a href="/articles/peptic-ulcers">duodenal ulcers</a>: occur most frequently in the duodenal bulb</li>-<li>AIDS</li>-<li>post-radiation therapy</li>-</ul><h6>Infective</h6><ul>-<li>-<em>Helicobacter pylori</em>: this has shown a near-universal relationship (>90%) with duodenal ulcers, an association with duodenitis remains unproven.</li>-<li><a href="/articles/giardiasis">giardiasis</a></li>-<li><a href="/articles/tropical-sprue">tropical sprue</a></li>- +<li><p><a href="/articles/peptic-ulcers">duodenal ulcers</a>: occur most frequently in the duodenal bulb</p></li>
- +<li><p><a href="/articles/aids-defining-illness-2" title="AIDS defining illness">AIDS</a></p></li>
- +<li><p>post-radiation therapy</p></li>
-<li><a href="/articles/non-steroidal-anti-inflammatory-drugs">NSAIDs</a></li>-<li>alcohol</li>-<li><a href="/articles/duodenal-diverticulitis">diverticulitis</a></li>-<li>gastric hypersecretion<ul><li>ectopic <a href="/articles/gastrinoma">gastrinoma</a> (<a href="/articles/zollinger-ellison-syndrome">Zollinger-Ellison syndrome</a>)</li></ul>- +<li><p><a href="/articles/non-steroidal-anti-inflammatory-drugs">NSAIDs</a></p></li>
- +<li><p>alcohol</p></li>
- +<li><p><a href="/articles/duodenal-diverticulitis">diverticulitis</a></p></li>
- +<li>
- +<p>gastric hypersecretion</p>
- +<ul><li><p>ectopic <a href="/articles/gastrinoma">gastrinoma</a> (<a href="/articles/zollinger-ellison-syndrome">Zollinger-Ellison syndrome</a>)</p></li></ul>
-</ul><h4>Radiographic features</h4><p>Findings include thickening of folds (if present they are almost always found proximal to the <a href="/articles/ampulla-of-vater-1">ampulla of Vater</a>), nodules or nodular folds, and erosions. Deformity of the <a href="/articles/duodenal-bulb">duodenal bulb</a> also may be seen.</p><h4>Differential Diagnosis</h4><ul><li><p><a href="/articles/brunner-gland-hyperplasia-1">Brunner’s gland hyperplasia</a>: is the main consideration but is likely a rare disorder</p></li></ul>- +</ul><h4>Radiographic features</h4><p>Findings include thickening of folds (if present, they are almost always found proximal to the <a href="/articles/ampulla-of-vater-1">ampulla of Vater</a>), nodules or nodular folds, and erosions. Deformity of the <a href="/articles/duodenal-bulb">duodenal bulb</a> also may be seen.</p><h4>Differential diagnosis</h4><ul><li><p><a href="/articles/brunner-gland-hyperplasia-1">Brunner gland hyperplasia</a>: the main consideration but a rare disorder</p></li></ul>
Images Changes:
Image 1 Pathology ( update )
Caption
was changed:
Figure 1: CMVhistology (CMV duodenitis: histology)
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