Empty light bulb sign (brain death)

Changed by Mostafa Elfeky, 25 Apr 2019

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Body was changed:

In brain death, on Tc-99m HMPAO-Tc99m imaging there is absent or reduced flow in the internal carotid arteries and increased flow within the external carotid arteries. This leads to absent uptake in the brain with subsequent increased perfusion in the nasal region. This appearance has been called the empty light bulb sign

It has also been described as the hot nose sign.

  • -<p>In brain death, on HMPAO-Tc99m imaging there is absent or reduced flow in the <a href="/articles/internal-carotid-artery-1">internal carotid arteries</a> and increased flow within the <a href="/articles/external-carotid-artery-1">external carotid arteries</a>. This leads to absent uptake in the brain with subsequent increased perfusion in the nasal region. This appearance has been called the <strong>empty light bulb sign</strong>. </p><p>It has also been described as the <a href="/articles/hot-nose-sign">hot nose sign</a>.</p>
  • +<p>In brain death, on <a title="Tc-99m HMPAO labelled WBC" href="/articles/tc-99m-hmpao-labelled-wbc">Tc-99m HMPAO</a> imaging there is absent or reduced flow in the <a href="/articles/internal-carotid-artery-1">internal carotid arteries</a> and increased flow within the <a href="/articles/external-carotid-artery-1">external carotid arteries</a>. This leads to absent uptake in the brain with subsequent increased perfusion in the nasal region. This appearance has been called the <strong>empty light bulb sign</strong>. </p><p>It has also been described as the <a href="/articles/hot-nose-sign">hot nose sign</a>.</p>

References changed:

  • 1. Kizilca Ö, Öztek A, Kesimal U, Şenol U. Signs in Neuroradiology: A Pictorial Review. (2017) Korean journal of radiology. 18 (6): 992-1004. <a href="https://doi.org/10.3348/kjr.2017.18.6.992">doi:10.3348/kjr.2017.18.6.992</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/29089832">Pubmed</a> <span class="ref_v4"></span>

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