Extramedullary hematopoiesis in the adrenal gland
Updates to Article Attributes
Extramedullary haematopoiesis in in the adrenal gland is a rare physiologic compensatory event in many haematologic diseases.
For a general discussion on this subject, please refer to the main article on extramedullary haematopoiesis.
Epidemiology
ExtramedullarExtramedullary haematopoiesis in the adrenal gland is uncommon 2. Instead, it occurs most commonly in the spleen, liver, and lymph nodes and less frequently in the lung, pleura, breast, thymus, small bowel, and central nervous system 1.
Pathology
The adrenal glands might be involved unilaterally or bilaterally 4. Although rare, there are few reports describing extramedullarextramedullary haematopoiesis in the adrenal gland in patients with thalassaemia 3.
The exact mechanism of extramedullarextramedullary haematopoiesis in the adrenal gland is unknown. Several hypotheses include 5:
- adrenal gland has haematopoietic capacity during the fetal period and
extramedullarextramedullary haematopoiesis may develop from primitive restsin diseased condition - embolisation of hematopoietic stem cells in adrenal gland may occur
- there may be chronic hypoxia 4,6
-<p><strong><a href="/articles/extramedullary-haematopoiesis">Extramedullary haematopoiesis</a> in the adrenal gland</strong> is a rare physiologic compensatory event in many haematologic diseases.</p><h4>Epidemiology</h4><p>Extramedullar haematopoiesis in the <a title="Adrenal gland" href="/articles/adrenal-gland">adrenal gland</a> is uncommon <sup>2</sup>. Instead, it occurs most commonly in the spleen, liver, and lymph nodes and less frequently in the lung, pleura, breast, thymus, small bowel, and central nervous system <sup>1</sup>.</p><h4>Pathology</h4><p>The adrenal glands might be involved unilaterally or bilaterally <sup>4</sup>. Although rare, there are few reports describing extramedullar haematopoiesis in the adrenal gland in patients with <a title="Thalassaemia" href="/articles/thalassaemia">thalassaemia</a> <sup>3</sup>.</p><p>The exact mechanism of extramedullar haematopoiesis in the adrenal gland is unknown. Several hypotheses include <sup>5</sup>:</p><ul>-<li>adrenal gland has haematopoietic capacity during the fetal period and extramedullar haematopoiesis may develop from primitive rests in diseased condition</li>- +<p><strong>Extramedullary haematopoiesis in the adrenal gland</strong> is a rare physiologic compensatory event in many haematologic diseases.</p><p>For a general discussion on this subject, please refer to the main article on <a title="Extramedullary haematopoiesis" href="/articles/extramedullary-haematopoiesis">extramedullary haematopoiesis</a>.</p><h4>Epidemiology</h4><p>Extramedullary haematopoiesis in the <a href="/articles/adrenal-gland">adrenal gland</a> is uncommon <sup>2</sup>. Instead, it occurs most commonly in the spleen, liver, and lymph nodes and less frequently in the lung, pleura, breast, thymus, small bowel, and central nervous system <sup>1</sup>.</p><h4>Pathology</h4><p>The adrenal glands might be involved unilaterally or bilaterally <sup>4</sup>. Although rare, there are few reports describing extramedullary haematopoiesis in the adrenal gland in patients with <a href="/articles/thalassaemia">thalassaemia</a> <sup>3</sup>.</p><p>The exact mechanism of extramedullary haematopoiesis in the adrenal gland is unknown. Several hypotheses include <sup>5</sup>:</p><ul>
- +<li>adrenal gland has haematopoietic capacity during the fetal period and extramedullary haematopoiesis may develop from primitive rests</li>
Unable to process the form. Check for errors and try again.