Fetal ductus venosus flow assessment

Changed by Daniel J Bell, 21 Apr 2023
Disclosures - updated 19 Aug 2022: Nothing to disclose

Updates to Article Attributes

Body was changed:

Fetal ductus venosus flow assessment can be useful in a number of situations in fetal ultrasound:

Of all the pre-cardiacprecardiac veins, the ductus venosus allows the most accurate interpretation of fetal cardiac function as well as myocardial haemodynamics 9.

Radiographic assessment

Ultrasound
Technique
  • the fetus should be as still as possible

    • variability in the heights of the S and D waves may indicate fetal breathing, which is normal, but wait for the fetus to be more still before evaluating

  • the probe is ideally focussedfocused so sampling is done where the umbilical vein joins the ductus venosus

  • a right ventral mid-sagittal view of the fetal trunk should be obtained and colour flow mapping used to demonstrate the umbilical vein, ductus venosus and fetal heart

  • the probe is ideally angled to allow a mid sagittal plane or a transverse oblique plane through the fetal abdomen

  • the image should be magnified enough for the fetal thorax and abdomen to occupy the whole screen

  • do not contaminate the ductus venosus flow with the flow from the fetal inferior vena cava, for this the Doppler sample should be small (0.5-1 mm)

  • the insonation angle should be 30° or less

  • the sweep speed should be high (2-3 cm/s) so that the waveforms are spread allowing better assessment of the A wave 

  • set the wall filter low enough so that the A wave is not obscured 10

On Doppler ultrasound, the flow in the ductus venosus has a characteristic triphasic waveform where in a normal physiological situation flow should always be in the forward direction 7 (i.e. towards the fetal heart).

This triphasic waveform comprises of:

  • S wave: corresponds to fetal ventricular systolic contraction and is the highest peak

  • D wave: corresponds to fetal early ventricular diastole and is the second highest peak

  • A wave: corresponds to fetal atrial contraction and is the lowest point in the wave form albeit still being in the forward direction

    • as above, reversal of the A wave (i.e. crossing the baseline) is always abnormal 10

See also

  • -<p><strong>Fetal ductus venosus flow assessment </strong>can be useful in a number of situations in fetal ultrasound:</p><ul>
  • -<li>first-trimester screening for <a href="/articles/aneuploidic-anomalies">aneuploidic anomalies</a>
  • -</li>
  • -<li>second and third-trimester scanning when there are concerns regarding<ul>
  • -<li><a href="/articles/intrauterine-growth-restriction">intrauterine growth restriction (IUGR)</a></li>
  • -<li><a href="/articles/fetal-cardiac-compromise">fetal cardiac compromise</a></li>
  • -</ul>
  • -</li>
  • -</ul><p>Of all the pre-cardiac veins, the <a href="/articles/ductus-venosus">ductus </a><a href="/articles/ductus-venosus">venosus</a> allows the most accurate interpretation of fetal cardiac function as well as myocardial haemodynamics <sup>9</sup>.</p><h4>Radiographic assessment</h4><h5>Ultrasound</h5><h6>Technique</h6><ul>
  • -<li>the fetus should be as still as possible<ul><li>variability in the heights of the S and D waves may indicate fetal breathing, which is normal, but wait for the fetus to be more still before evaluating</li></ul>
  • -</li>
  • -<li>the probe is ideally focussed so sampling is done where the <a href="/articles/umbilical-vein">umbilical vein</a> joins the <a href="/articles/ductus-venosus">ductus venosus</a>
  • -</li>
  • -<li>a right ventral mid-sagittal view of the fetal trunk should be obtained and colour flow mapping used to demonstrate the umbilical vein, ductus venosus and fetal heart</li>
  • -<li>the probe is ideally angled to allow a mid sagittal plane or a transverse oblique plane through the fetal abdomen</li>
  • -<li>the image should be magnified enough for the fetal thorax and abdomen to occupy the whole screen</li>
  • -<li>do not contaminate the ductus venosus flow with the flow from the fetal <a href="/articles/inferior-vena-cava-1">inferior vena cava</a>, for this the Doppler sample should be small (0.5-1 mm)</li>
  • -<li>the insonation angle should be 30° or less</li>
  • -<li>the sweep speed should be high (2-3 cm/s) so that the waveforms are spread allowing better assessment of the A wave </li>
  • -<li>set the wall filter low enough so that the A wave is not obscured <sup>10</sup>
  • -</li>
  • -</ul><p>On Doppler ultrasound, the flow in the ductus venosus has a characteristic <strong>triphasic</strong> waveform where in a <strong>normal physiological situation</strong> flow should always be in the forward direction <sup>7</sup> (i.e. towards the fetal heart).</p><p>This triphasic waveform comprises of:</p><ul>
  • -<li>
  • -<strong>S wave:</strong> corresponds to fetal ventricular systolic contraction and is the highest peak</li>
  • -<li>
  • -<strong>D wave:</strong> corresponds to fetal early ventricular diastole and is the second highest peak</li>
  • -<li>
  • -<strong>A wave:</strong> corresponds to fetal atrial contraction and is the lowest point in the wave form albeit still being in the forward direction<ul><li>as above, reversal of the A wave (i.e. crossing the baseline) is always abnormal <sup>10</sup>
  • -</li></ul>
  • -</li>
  • -</ul><h4>See also</h4><ul><li><a href="/articles/ductus-venosus">ductus venosus</a></li></ul>
  • +<p><strong>Fetal ductus venosus flow assessment </strong>can be useful in a number of situations in fetal ultrasound:</p><ul>
  • +<li><p>first-trimester screening for <a href="/articles/aneuploidic-anomalies">aneuploidic anomalies</a></p></li>
  • +<li>
  • +<p>second and third-trimester scanning when there are concerns regarding</p>
  • +<ul>
  • +<li><p><a href="/articles/intrauterine-growth-restriction">intrauterine growth restriction (IUGR)</a></p></li>
  • +<li><p><a href="/articles/fetal-cardiac-compromise">fetal cardiac compromise</a></p></li>
  • +</ul>
  • +</li>
  • +</ul><p>Of all the precardiac veins, the <a href="/articles/ductus-venosus">ductus venosus</a> allows the most accurate interpretation of fetal cardiac function as well as myocardial haemodynamics <sup>9</sup>.</p><h4>Radiographic assessment</h4><h5>Ultrasound</h5><h6>Technique</h6><ul>
  • +<li>
  • +<p>the fetus should be as still as possible</p>
  • +<ul><li><p>variability in the heights of the S and D waves may indicate fetal breathing, which is normal, but wait for the fetus to be more still before evaluating</p></li></ul>
  • +</li>
  • +<li><p>the probe is ideally focused so sampling is done where the <a href="/articles/umbilical-vein">umbilical vein</a> joins the <a href="/articles/ductus-venosus">ductus venosus</a></p></li>
  • +<li><p>a right ventral mid-sagittal view of the fetal trunk should be obtained and colour flow mapping used to demonstrate the umbilical vein, ductus venosus and fetal heart</p></li>
  • +<li><p>the probe is ideally angled to allow a mid sagittal plane or a transverse oblique plane through the fetal abdomen</p></li>
  • +<li><p>the image should be magnified enough for the fetal thorax and abdomen to occupy the whole screen</p></li>
  • +<li><p>do not contaminate the ductus venosus flow with the flow from the fetal <a href="/articles/inferior-vena-cava-1">inferior vena cava</a>, for this the Doppler sample should be small (0.5-1 mm)</p></li>
  • +<li><p>the insonation angle should be 30° or less</p></li>
  • +<li><p>the sweep speed should be high (2-3 cm/s) so that the waveforms are spread allowing better assessment of the A wave </p></li>
  • +<li><p>set the wall filter low enough so that the A wave is not obscured <sup>10</sup></p></li>
  • +</ul><p>On Doppler ultrasound, the flow in the ductus venosus has a characteristic <strong>triphasic</strong> waveform where in a <strong>normal physiological situation</strong> flow should always be in the forward direction <sup>7</sup> (i.e. towards the fetal heart).</p><p>This triphasic waveform comprises of:</p><ul>
  • +<li><p><strong>S wave:</strong> corresponds to fetal ventricular systolic contraction and is the highest peak</p></li>
  • +<li><p><strong>D wave:</strong> corresponds to fetal early ventricular diastole and is the second highest peak</p></li>
  • +<li>
  • +<p><strong>A wave:</strong> corresponds to fetal atrial contraction and is the lowest point in the wave form albeit still being in the forward direction</p>
  • +<ul><li><p>as above, reversal of the A wave (i.e. crossing the baseline) is always abnormal <sup>10</sup></p></li></ul>
  • +</li>
  • +</ul><h4>See also</h4><ul><li><p><a href="/articles/ductus-venosus">ductus venosus</a></p></li></ul>

References changed:

  • 1. Maiz N, Plasencia W, Dagklis T, Faros E, Nicolaides K. Ductus Venosus Doppler in Fetuses with Cardiac Defects and Increased Nuchal Translucency Thickness. Ultrasound Obstet Gynecol. 2008;31(3):256-60. <a href="https://doi.org/10.1002/uog.5262">doi:10.1002/uog.5262</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/18307193">Pubmed</a>
  • 2. Huisman T, Brezinka C, Stewart P, Stijnen T, Wladimiroff J. Ductus Venosus Flow Velocity Waveforms in Relation to Fetal Behavioural States. BJOG:An International Journal of O&G. 1994;101(3):220-4. <a href="https://doi.org/10.1111/j.1471-0528.1994.tb13113.x">doi:10.1111/j.1471-0528.1994.tb13113.x</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/8193096">Pubmed</a>
  • 3. Huisman T, Stewart P, Wladimiroff J. Ductus Venosus Blood Flow Velocity Waveforms in the Human Fetus—A Doppler Study. Ultrasound in Medicine & Biology. 1992;18(1):33-7. <a href="https://doi.org/10.1016/0301-5629(92)90005-u">doi:10.1016/0301-5629(92)90005-u</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/1566523">Pubmed</a>
  • 4. Huisman T. Doppler Assessment of the Fetal Venous System. Semin Perinatol. 2001;25(1):21-31. <a href="https://doi.org/10.1053/sper.2001.22890">doi:10.1053/sper.2001.22890</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/11254156">Pubmed</a>
  • 5. Barry B. Goldberg, John P. McGahan. Atlas of Ultrasound Measurements. (2006) ISBN: 032303229X - <a href="http://books.google.com/books?vid=ISBN032303229X">Google Books</a>
  • 6. Sherer D. Prenatal Ultrasonographic Assessment of the Ductus Venosus: A Review. Obstetrics & Gynecology. 1996;88(4):626-32. <a href="https://doi.org/10.1016/0029-7844(96)00181-0">doi:10.1016/0029-7844(96)00181-0</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/8841232">Pubmed</a>
  • 9. Eberhard Merz. Ultrasound in Obstetrics and Gynecology. (2005) ISBN: 9781588901477 - <a href="http://books.google.com/books?vid=ISBN9781588901477">Google Books</a>
  • 10. Kennedy A & Woodward P. A Radiologist’s Guide to the Performance and Interpretation of Obstetric Doppler US. Radiographics. 2019;39(3):893-910. <a href="https://doi.org/10.1148/rg.2019180152">doi:10.1148/rg.2019180152</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31059392">Pubmed</a>
  • 1. Maiz N, Plasencia W, Dagklis T, Faros E, Nicolaides K. Ductus Venosus Doppler in Fetuses with Cardiac Defects and Increased Nuchal Translucency Thickness. Ultrasound Obstet Gynecol. 2008;31(3):256-260. <a href="https://doi.org/10.1002/uog.5262">doi:10.1002/uog.5262</a>
  • 2. Huisman T, Brezinka C, Stewart P, Stijnen T, Wladimiroff J. Ductus Venosus Flow Velocity Waveforms in Relation to Fetal Behavioural States. BJOG:An international journal of O&G. 1994;101(3):220-224. <a href="https://doi.org/10.1111/j.1471-0528.1994.tb13113.x">doi:10.1111/j.1471-0528.1994.tb13113.x</a>
  • 3. Huisman T, Stewart P, Wladimiroff J. Ductus Venosus Blood Flow Velocity Waveforms in the Human Fetus—A Doppler Study. Ultrasound in Medicine & Biology. 1992;18(1):33-37. <a href="https://doi.org/10.1016/0301-5629(92)90005-u">doi:10.1016/0301-5629(92)90005-u</a>
  • 4. Huisman T. Doppler Assessment of the Fetal Venous System. Semin Perinatol. 2001;25(1):21-31. <a href="https://doi.org/10.1053/sper.2001.22890">doi:10.1053/sper.2001.22890</a>
  • 5. McGahan, John P.. Atlas of Ultrasound Measurements. (2006) ISBN: 032303229X - <a href="http://books.google.com/books?vid=ISBN032303229X">Google Books</a>
  • 6. Sherer D. Prenatal Ultrasonographic Assessment of the Ductus Venosus: A Review. Obstetrics & Gynecology. 1996;88(4):626-632. <a href="https://doi.org/10.1016/0029-7844(96)00181-0">doi:10.1016/0029-7844(96)00181-0</a>
  • 9. F. Bahlmann (Contributor), R. Bollmann (Contributor), R. Chaoui (Contributor). Eberhard Merz. Ultrasound in Obstetrics and GynecologyDiagnostic Ultrasound In. (2005) ISBN: 9781588901477 - <a href="http://books.google.com/books?vid=ISBN9781588901477">Google Books</a>
  • 10. Kennedy A & Woodward P. A Radiologist’s Guide to the Performance and Interpretation of Obstetric Doppler US. Radiographics. 2019;39(3):893-910. <a href="https://doi.org/10.1148/rg.2019180152">doi:10.1148/rg.2019180152</a>

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