Gastric cancer (TNM staging)

Changed by Chunggung Kuo, 23 Oct 2021

Updates to Article Attributes

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Gastric cancer staging is routinely performed using the TNM staging system. This article is based on the 7th edition of the TNM classification of malignant tumours.

TNM staging (7th edition)

T
  • T1
    • T1a: tumour invades the lamina propria and or muscularis mucosae 
    • T1b: tumour invades submucosa 
  • T2: tumour invades muscularis propria 
  • T3: tumour penetrates the serosa without invasion of the adjacent structures
  • T4
    • T4a: tumour invades serosa (visceral peritoneum)
    • T4b: tumour invades adjacent structures
  N
  • N0: no nodal involvement
  • N1: metastases in 1 to 2 regional lymph nodes
  • N2: metastases in 3 to 6 regional lymph nodes
  • N3
    • N3a: metastases in 7 to 15 regional lymph nodes
    • N3b: metastases in more than 15 regional lymph nodes
M
  • M0: no distant metastases
  • M1: distant metastases

TNM staging (8th edition)

T

  • Tx: primary tumor cannot be assessed
  • T0: no evidence of primary tumor
  • Tis: carcinoma in situ: intraepithelial tumor without invasion of the lamina propria, high grade dysplasia
  • T1
    • T1a: tumour invades the lamina propria and or muscularis mucosae 
    • T1b: tumour invades submucosa 
  • T2: tumour invades muscularis propria 
  • T3: Tumor penetrates the subserosal connective tissue without invasion of the visceral peritoneum or adjacent structures
  • T4
    • T4a: tumour invades serosa (visceral peritoneum)
    • T4b: tumour invades adjacent structures

  N

  • Nx: regional lymph node (s) cannot be assessed
  • N0: no regional nodal involvement
  • N1: metastases in 1 to 2 regional lymph nodes
  • N2: metastases in 3 to 6 regional lymph nodes
  • N3
    • N3a: metastases in 7 to 15 regional lymph nodes
    • N3b: metastases in more than 15 regional lymph nodes

M

  • M0: no distant metastases
  • M1: distant metastases

***Reference for AJCC 8th to be added***

  • -<p><strong>Gastric cancer staging</strong> is routinely performed using the <a href="/articles/tnm-staging-system">TNM staging system</a>. This article is based on the 7th edition of the TNM classification of malignant tumours.</p><h4>TNM staging (7<sup>th </sup>edition)</h4><h5><strong>T</strong></h5><ul>
  • +<p><strong>Gastric cancer staging</strong> is routinely performed using the <a href="/articles/tnm-staging-system-2">TNM staging system</a>. This article is based on the 7th edition of the TNM classification of malignant tumours.</p><h4>TNM staging (7<sup>th </sup>edition)</h4><h5><strong>T</strong></h5><ul>
  • -</ul>
  • +</ul><p> </p><p> </p><p><strong>TNM staging (8th edition)</strong></p><p>T</p><ul>
  • +<li>Tx: primary tumor cannot be assessed</li>
  • +<li>T0: no evidence of primary tumor</li>
  • +<li>Tis: carcinoma in situ: intraepithelial tumor without invasion of the lamina propria, high grade dysplasia</li>
  • +<li>T1<ul>
  • +<li>T1a: tumour invades the lamina propria and or muscularis mucosae </li>
  • +<li>T1b: tumour invades submucosa </li>
  • +</ul>
  • +</li>
  • +<li>T2: tumour invades muscularis propria </li>
  • +<li>T3: Tumor penetrates the subserosal connective tissue without invasion of the visceral peritoneum or adjacent structures</li>
  • +<li>T4<ul>
  • +<li>T4a: tumour invades serosa (visceral peritoneum)</li>
  • +<li>T4b: tumour invades adjacent structures</li>
  • +</ul>
  • +</li>
  • +</ul><p>  N</p><ul>
  • +<li>Nx: regional lymph node (s) cannot be assessed</li>
  • +<li>N0: no regional nodal involvement</li>
  • +<li>N1: metastases in 1 to 2 regional lymph nodes</li>
  • +<li>N2: metastases in 3 to 6 regional lymph nodes</li>
  • +<li>N3<ul>
  • +<li>N3a: metastases in 7 to 15 regional lymph nodes</li>
  • +<li>N3b: metastases in more than 15 regional lymph nodes</li>
  • +</ul>
  • +</li>
  • +</ul><p>M</p><ul>
  • +<li>M0: no distant metastases</li>
  • +<li>M1: distant metastases</li>
  • +</ul><p>***Reference for AJCC 8th to be added***</p>

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