Gilbert syndrome
Updates to Article Attributes
Body
was changed:
Gilbert syndrome is a hereditary condition which can result in jaundice.
Pathology
It is results in intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or haemolysis. Uridine diphosphate-glucuronyl transferase activity is reduced resulting in indirect hyperbilirubinemia.
Genetics
It carries an autosomal dominant inheritance with incomplete penetrance.
-<p><strong>Gilbert syndrome</strong> is a hereditary condition which can result in <a title="Jaundice" href="/articles/jaundice">jaundice</a>.</p><h4>Pathology</h4><p>It is results in intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or haemolysis. Uridine diphosphate-glucuronyl transferase activity is reduced resulting in indirect hyperbilirubinemia. </p><h5>Genetics</h5><p>It carries an autosomal dominant inheritance with incomplete penetrance.</p><p> </p>- +<p><strong>Gilbert syndrome</strong> is a hereditary condition which can result in <a href="/articles/jaundice">jaundice</a>.</p><h4>Pathology</h4><p>It is results in intermittent unconjugated hyperbilirubinemia in the absence of hepatocellular disease or haemolysis. Uridine diphosphate-glucuronyl transferase activity is reduced resulting in indirect hyperbilirubinemia. </p><h5>Genetics</h5><p>It carries an autosomal dominant inheritance with incomplete penetrance.</p><p> </p>
References changed:
- 1. Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 143500: Accessed 24/08/2023. <a href="https://omim.org/entry/143500">OMIM</a> <span class="ref_v4"></span>
- 2. Burchell B & Hume R. Molecular Genetic Basis of Gilbert's Syndrome. J Gastroenterol Hepatol. 1999;14(10):960-6. <a href="https://doi.org/10.1046/j.1440-1746.1999.01984.x">doi:10.1046/j.1440-1746.1999.01984.x</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/10530490">Pubmed</a>
Systems changed:
- Hepatobiliary
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