Glycogenic acanthosis
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was changed:
Glycogenic acanthosis is a benign finding on oesophagography in elderly patients.
Epidemiology
It most commonly occurs in patients >40Y;40 years of age. No gender predilection.
Pathology
It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with gastro-oesophageal reflux.
Radiologic findings
- multiple small nodules and plaques measuring 2
-15-10 mm - plaques are randomly distributed
- often in the upper to mid thoracic oesophagus
- the appearance can appear similar to other forms of oesophagitis, but is asymptomatic
Differential diagnosis
-<p><strong>Glycogenic acanthosis</strong> is a benign finding on oesophagography in elderly patients.</p><h4>Epidemiology</h4><p>It most commonly occurs in patients >40Y. No gender predilection.</p><h4>Pathology</h4><p>It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with <a title="Gastro-oesophageal reflux disease" href="/articles/gastro-oesophageal-reflux-disease">gastro-oesophageal reflux</a>.</p><h4>Radiologic findings</h4><ul>-<li>multiple small nodules and plaques measuring 2-15 mm</li>- +<p><strong>Glycogenic acanthosis</strong> is a benign finding on oesophagography in elderly patients.</p><h4>Epidemiology</h4><p>It most commonly occurs in patients >40 years of age. No gender predilection.</p><h4>Pathology</h4><p>It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with <a href="/articles/gastro-oesophageal-reflux-disease">gastro-oesophageal reflux</a>.</p><h4>Radiologic findings</h4><ul>
- +<li>multiple small nodules and plaques measuring 2-10 mm</li>
- +<li>often in the upper to mid thoracic oesophagus</li>
-</ul><h4>Differential diagnosis</h4><ul><li><a title="Granular mucosal pattern of the oesophagus (differential)" href="/articles/granular-mucosal-pattern-of-the-oesophagus-differential">granular mucosal pattern of the oesophagus (differential)</a></li></ul>- +</ul><h4>Differential diagnosis</h4><ul>
- +<li><a href="/articles/granular-mucosal-pattern-of-the-oesophagus-differential">granular mucosal pattern of the oesophagus (differential)</a></li>
- +<li><a title="squamous papillomatosis of the oesophagus" href="/articles/squamous-papillomatosis-of-the-oesophagus">squamous papillomatosis of the oesophagus</a></li>
- +</ul>
References changed:
- 1. Tsai SJ, Lin CC, Chang CW et-al. Benign esophageal lesions: endoscopic and pathologic features. World J. Gastroenterol. 2015;21 (4): 1091-8. <a href="http://dx.doi.org/10.3748/wjg.v21.i4.1091">doi:10.3748/wjg.v21.i4.1091</a> - <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306152">Free text at pubmed</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/25632181">Pubmed citation</a><span class="auto"></span>
- 2. Nazligül Y, Aslan M, Esen R et-al. Benign glycogenic acanthosis lesions of the esophagus. Turk J Gastroenterol. 2013;23 (3): 199-202. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22798107">Pubmed citation</a><span class="auto"></span>
- 3. Rose D, Furth EE, Rubesin SE. Glycogenic acanthosis. AJR Am J Roentgenol. 1995;164 (1): 96. <a href="http://www.ajronline.org/content/164/1/96">AJR Am J Roentgenol (citation)</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/7998577">Pubmed citation</a><span class="ref_v3"></span>
Tags changed:
- barium swallow
- oesophagography
- oesophagus
- normal variant
- cases
Systems changed:
- Gastrointestinal
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