Glycogenic acanthosis
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Glycogenic acanthosis is a benign finding on oesophagography in elderly patients.
Epidemiology
It most commonly occurs in patients >40 years of age. No gender predilection.
Pathology
It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with gastro-oesophageal reflux.
Radiologic findingsRadiographic features
- multiple small nodules and plaques measuring 2-10 mm
- plaques are randomly distributed
- often in the upper to mid thoracic oesophagus
- the appearance can appear similar to other forms of oesophagitis, but is asymptomatic
Differential diagnosis
-<p><strong>Glycogenic acanthosis</strong> is a benign finding on oesophagography in elderly patients.</p><h4>Epidemiology</h4><p>It most commonly occurs in patients >40 years of age. No gender predilection.</p><h4>Pathology</h4><p>It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with <a href="/articles/gastro-oesophageal-reflux-disease">gastro-oesophageal reflux</a>.</p><h4>Radiologic findings</h4><ul>- +<p><strong>Glycogenic acanthosis</strong> is a benign finding on oesophagography in elderly patients.</p><h4>Epidemiology</h4><p>It most commonly occurs in patients >40 years of age. No gender predilection.</p><h4>Pathology</h4><p>It occurs from a combination of cellular hyperplasia and increased cellular glycogen in squamous epithelial cells lining the oesophagus. The oesophageal mucosa is otherwise normal. It is not thought to be associated with <a href="/articles/gastro-oesophageal-reflux-disease">gastro-oesophageal reflux</a>.</p><h4>Radiographic features</h4><ul>
-<li><a title="squamous papillomatosis of the oesophagus" href="/articles/squamous-papillomatosis-of-the-oesophagus">squamous papillomatosis of the oesophagus</a></li>- +<li><a href="/articles/squamous-papillomatosis-of-the-oesophagus">squamous papillomatosis of the oesophagus</a></li>
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