Hepatic chemosaturation
Updates to Article Attributes
Body
was changed:
Hepatic chemosaturation is a percutaneous technique used to locally treat unresectable hepatic metastases in patients without systemic disease.
Technique
The key to this technique is isolating the blood supply to the liver. This is achieved by:
- closure of the gastro-duodenal artery by coiling
- blocking the IVC with a balloon
Following this very high dose of chemotherapy (melphalan) is injected 'saturating' the liver.
Complications
- systemic toxicity: decrease blood cell count
- liver damage: deranged liver enzymes
-<p><strong>Hepatic chemosaturation</strong> is a percutaneous technique used to locally treat unresectable <a title="Hepatic metastases" href="/articles/hepatic-metastases-1">hepatic metastases</a> in patients without systemic disease. </p><p> </p><h4>Technique</h4><p>The key to this technique is isolating the blood supply to the liver. This is achieved by:</p><ul>- +<p><strong>Hepatic chemosaturation</strong> is a percutaneous technique used to locally treat unresectable <a href="/articles/hepatic-metastases-1">hepatic metastases</a> in patients without systemic disease.</p><h4>Technique</h4><p>The key to this technique is isolating the blood supply to the liver. This is achieved by:</p><ul>
-</ul><p>Following this very high dose of chemotherapy (melphalan) is injected 'saturating' the liver. </p><h4><strong>Complications</strong></h4><ul>- +</ul><p>Following this very high dose of chemotherapy (melphalan) is injected 'saturating' the liver. </p><h4>Complications</h4><ul>
-</ul><p> </p>- +</ul>
References changed:
- 1. Vogl TJ, Zangos S, Scholtz JE et-al. Chemosaturation with Percutaneous Hepatic Perfusions of Melphalan for Hepatic Metastases: Experience from Two European Centers. Rofo. . <a href="http://dx.doi.org/10.1055/s-0034-1366081">doi:10.1055/s-0034-1366081</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/24729409">Pubmed citation</a><span class="auto"></span>
- Vogl TJ, Zangos S, Scholtz JE et-al. Chemosaturation with Percutaneous Hepatic Perfusions of Melphalan for Hepatic Metastases: Experience from Two European Centers. Rofo. . <a href="http://dx.doi.org/10.1055/s-0034-1366081">doi:10.1055/s-0034-1366081</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/24729409">Pubmed citation</a><span class="auto"></span>
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