Holman-Miller sign (maxillary sinus)

Changed by Daniel J Bell, 18 Dec 2017

Updates to Article Attributes

Body was changed:

The Holman-Miller sign (also called the antral sign) is seen in juvenile nasopharyngeal angiofibroma; it refers to the anterior bowing of the posterior wall of the maxillary antrum as seen on a lateral skull radiograph or cross-sectional imaging 1,2.

This is a non-specific sign that can be produced by any slowly-growing mass, whereas erosion of the pterygoid lamina maybe pathognomonic for juvenile nasopharyngeal angiofibroma 3.

History and etymology

Colin B Holman (1917-2008) 5 and W Eugene "Gene" Miller (d 2013), American radiologists, described their eponymous sign on plain radiographs in a paper in 1965 4.

  • -<p>The<strong> Holman-Miller sign</strong> (also called the <strong>antral sign</strong>) is seen in <a href="/articles/juvenile-nasopharyngeal-angiofibroma">juvenile nasopharyngeal angiofibroma</a>; it refers to the anterior bowing of the posterior wall of the maxillary antrum as seen on a <a title="Lateral skull radiograph" href="/articles/skull-lateral-view-1">lateral skull radiograph</a> or <a title="Cross-sectional imaging" href="/articles/cross-sectional-imaging-1">cross-sectional imaging</a> <sup>1,2</sup>.</p><p>This is a non-specific sign that can be produced by any slowly-growing mass, whereas erosion of the pterygoid lamina maybe pathognomonic for juvenile nasopharyngeal angiofibroma <sup>3</sup>.</p>
  • +<p>The<strong> Holman-Miller sign</strong> (also called the <strong>antral sign</strong>) is seen in <a href="/articles/juvenile-nasopharyngeal-angiofibroma">juvenile nasopharyngeal angiofibroma</a>; it refers to the anterior bowing of the posterior wall of the maxillary antrum as seen on a <a href="/articles/skull-lateral-view-1">lateral skull radiograph</a> or <a href="/articles/cross-sectional-imaging-1">cross-sectional imaging</a> <sup>1,2</sup>.</p><p>This is a non-specific sign that can be produced by any slowly-growing mass, whereas erosion of the pterygoid lamina maybe pathognomonic for juvenile nasopharyngeal angiofibroma <sup>3</sup>.</p><h4>History and etymology</h4><p><strong>Colin B Holman</strong> (1917-2008) <sup>5</sup> and <strong>W Eugene "Gene" Miller </strong>(d 2013), American radiologists, described their eponymous sign on plain radiographs in a paper in 1965 <sup>4</sup>.</p>

References changed:

  • 4. Holman CB and Miller WE. Juvenile nasopharyngeal fibroma: roentgenologic characteristics. American Journal of Roentgenol. Rad. Therapy & Nuclear Med 1965;94:292-298.
  • 4. Holman CB and Miller WE. Juvenile nasopharyngeal fibroma: roentgenologic characteristics. American Journal of Roentgenol. Rad. Therapy & Nuclear Med 1965;94:292-298.
  • 4. Holman CB and Miller WE. Juvenile nasopharyngeal fibroma: roentgenologic characteristics. American Journal of Roentgenol. Rad. Therapy & Nuclear Med 1965;94:292-298.
  • 5. Earnest F. Colin B. Holman. American Journal of Roentgenology. 2009;193: 1461-1462.
  • 5. Earnest F. Colin B. Holman. American Journal of Roentgenology. 2009;193: 1461-1462.
  • 4. Holman GB and Miller WH. Juvenile nasopharyngeal fibroma, roentgenologic characteristics. American Journal of Roentgenology 1965;94:292.
  • 4. Holman CB and Miller WE. Juvenile nasopharyngeal fibroma, roentgenologic characteristics. American Journal of Roentgenology 1965;94:292.
  • 5. Earnest F. Colin B. Holman. American Journal of Roentgenology. 2009;193: 1461-1462. DOI: 10.2214/AJR.09.3191.

Updates to Synonym Attributes

Title was changed:
Holman millerMiller sign

Updates to Synonym Attributes

Title was changed:
Holman millerMiller sign of juvenile nasopharyngeal angiofibroma

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.