Honeycombing (lungs)

Changed by Hoe Han Guan, 16 Jun 2022

Updates to Article Attributes

Body was changed:

Honeycombing is a CT imaging descriptor referring to clustered cystic air spaces (between 3-10 mm in diameter, but occasionally as large as 2.5 cm) that are usually subpleural, peripheral and basal in distribution. They can be subdivided into:

The walls of the cysts are well-defined and often thick (1-3 mm) 4. They represent an irreversible finding commonly seen in diffuse pulmonary fibrosis (usual interstitial pneumonia UIP). 

Pathology

Honeycombing consists of enlarged air spaces with thick fibrotic walls lined by bronchiolar epithelium and often filled with mucin and inflammatory cells 6.

History and etymology

The term “honeycomb lung” is thought to have originated in the 19th century in Germany and is thought to have first appeared in 1949 in a study by N Oswald and T Parkinson 5.

Differential diagnosis

  • -<li><a title="Bronchiolectasis" href="/articles/bronchiolectasis-1">traction bronchiolectasis</a></li>
  • +<li><a href="/articles/bronchiolectasis-1">traction bronchiolectasis</a></li>
  • -<a href="/articles/air-space-opacification-1">airspace consolidation</a> in the presence of <a title="Pulmonary emphysema" href="/articles/pulmonary-emphysema">pulmonary emphysema</a> can mimic this appearance</li>
  • +<a href="/articles/air-space-opacification-1">airspace consolidation</a> in the presence of <a href="/articles/pulmonary-emphysema">pulmonary emphysema</a> can mimic this appearance</li>
Images Changes:

Image 6 CT (lung window) ( create )

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.