Idiopathic interstitial pneumonia (mnemonic)

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Idiopathic interstitial pneumonias (IIPs) are diffuse interstitial lung diseases of unknown cause. They are characterized by infiltration of the interstitial compartment with inflammatory cells. A useful mnemonic for the American Thoracic Society-European Respiratory classification of IIPs is:

All Idiopathic Chronic Lung Disease aRe Nonspecific

The mnemonic reflects the frustration of trying to differentiate them on plain film. Indeed, diagnosis depends on HRCT findings, as well as clinical presentation. Even then, some cases require lung biopsy for definitive diagnosis.

Mnemonic

A: - acute interstitial pneumonia (AIP). The only acute process in the list.
I: - idiopathic pulmonary fibrosis / usual interstitial pneumonia (IPF / UIP)
C: cryptogenic organizing pneumonia(COP)
L: - lymphoid interstitial pneumonia (LIP)
D: - d esquamative interstitial pneumonia (DIP)
R: - r espiratory bronchiolitis–associated interstitial lung disease(RB-ILD)
N: - n on-specific interstitial pneumonia (NSIP)

The first two, AIP and IPF/UIP, have very poor prognosis. The next in the list, COP, is associated with good response to steroids and good prognosis. LIP is more common in women (think "LIPstick"), in contrast to the others, which are either more common in men or have equal gender distribution.

The following two, DIP and RB-ILD, are at extremes of a spectrum, are associated with smoking, and have good response with smoking cessation.

One caveat: The word chronic in the mnemonic should be taken with a grain of salt. Some of the entities may have a subacute presentation, and one, AIP, presents acutely.

-Idiopathic interstitial pneumonias (IIPs) are <a href="/articles/interstitial-lung-disease" title="Diffuse interstitial lung disease">diffuse interstitial lung diseases</a> of unknown cause. They are characterized by infiltration of the interstitial compartment with inflammatory cells. A useful mnemonic for the American Thoracic Society-European Respiratory classification of IIPs is:<ul><li>All Idiopathic Chronic Lung Disease aRe Nonspecific</li></ul>The mnemonic reflects the frustration of trying to differentiate them on plain film. Indeed, diagnosis depends on HRCT findings, as well as clinical presentation. Even then, some cases require lung biopsy for definitive diagnosis. <h4>Mnemonic</h4><ul>
~~-<li>~~
~~-A - <a href="/articles/acute-interstitial-pneumonia">acute interstitial pneumonia</a> (AIP). The only acute process in the list. </li>~~
~~-<li>~~
-I - <a href="/articles/idiopathic-pulmonary-fibrosis">idiopathic pulmonary fibrosis </a>/ <a href="/articles/usual-interstitial-pneumonia" title="usual interstitial pneumonia">usual interstitial pneumonia </a>(IPF / UIP) </li>
~~-<li>~~
-C -<a href="/articles/cryptogenic-organising-pneumonia-1" title=" cryptogenic organizing pneumonia "> </a><a href="/articles/cryptogenic-organising-pneumonia-1" title="Cryptogenic Organizing Pneumonia (COP)">cryptogenic organizing pneumonia</a><a href="/articles/cryptogenic-organising-pneumonia-1" title=" cryptogenic organizing pneumonia "> </a>(COP)</li>
~~-<li>~~
~~-L - <a href="/articles/lymphoid-interstitial-pneumonia">lymphoid interstitial pneumonia</a> (LIP) </li>~~
~~-<li>~~
~~-D - d<a href="/articles/desquamative-interstitial-pneumonia">esquamative interstitial pneumonia</a> (DIP) </li>~~
~~-<li>~~
-R - r<a href="/articles/respiratory-bronchiolitis-interstitial-lung-disease-1" title="Respiratory bronchiolitis ILD (RB-ILD)">espiratory bronchiolitis–associated interstitial lung disease</a> (RB-ILD) </li>
~~-<li>~~
~~-N - n<a href="/articles/non-specific-interstitial-pneumonia-1">on-specific interstitial pneumonia</a> (NSIP) </li>~~
-</ul>The first two, AIP and IPF/UIP, have very poor prognosis. The next in the list, COP, is associated with good response to steroids and good prognosis. LIP is more common in women (think "LIPstick"), in contrast to the others, which are either more common in men or have equal gender distribution. The following two, DIP and RB-ILD, are at extremes of a spectrum, are associated with smoking, and have good response with smoking cessation. One caveat : The word chronic in the mnemonic should be taken with a grain of salt. Some of the entities may have a subacute presentation, and one, AIP, presents acutely.
+Idiopathic interstitial pneumonias (IIPs) are <a href="/articles/interstitial-lung-disease">diffuse interstitial lung diseases</a> of unknown cause. They are characterized by infiltration of the interstitial compartment with inflammatory cells. A useful mnemonic for the American Thoracic Society-European Respiratory classification of IIPs is:<ul><li>All Idiopathic Chronic Lung Disease aRe Nonspecific</li></ul>The mnemonic reflects the frustration of trying to differentiate them on plain film. Indeed, diagnosis depends on HRCT findings, as well as clinical presentation. Even then, some cases require lung biopsy for definitive diagnosis.<h4>Mnemonic</h4><ul>
+<li>
+A: <a href="/articles/acute-interstitial-pneumonia">acute interstitial pneumonia</a> (AIP). The only acute process in the list.</li>
+<li>
+I: <a href="/articles/idiopathic-pulmonary-fibrosis">idiopathic pulmonary fibrosis </a>/ <a href="/articles/usual-interstitial-pneumonia">usual interstitial pneumonia </a>(IPF / UIP)</li>
+<li>
+C: <a href="/articles/cryptogenic-organising-pneumonia-1">cryptogenic organizing pneumonia</a><a href="/articles/cryptogenic-organising-pneumonia-1"> </a>(COP)</li>
+<li>
+L: <a href="/articles/lymphoid-interstitial-pneumonia">lymphoid interstitial pneumonia</a> (LIP)</li>
+<li>
+D: <a title="Desquamative interstitial pneumonia (DIP)" href="/articles/desquamative-interstitial-pneumonia">d</a><a href="/articles/desquamative-interstitial-pneumonia">esquamative interstitial pneumonia</a> (DIP)</li>
+<li>
+R: <a title="respiratory bronchiolitis–associated interstitial lung disease" href="/articles/respiratory-bronchiolitis-associated-interstitial-lung-disease">r</a><a href="/articles/respiratory-bronchiolitis-interstitial-lung-disease-1">espiratory bronchiolitis–associated interstitial lung disease</a><a title="respiratory bronchiolitis–associated interstitial lung disease" href="/articles/respiratory-bronchiolitis-associated-interstitial-lung-disease"> </a>(RB-ILD)</li>
+<li>
+N: <a title="Non-specific interstitial pneumonia" href="/articles/non-specific-interstitial-pneumonia-1">n</a><a href="/articles/non-specific-interstitial-pneumonia-1">on-specific interstitial pneumonia</a> (NSIP)</li>
+</ul>The first two, AIP and IPF/UIP, have very poor prognosis. The next in the list, COP, is associated with good response to steroids and good prognosis. LIP is more common in women (think "LIPstick"), in contrast to the others, which are either more common in men or have equal gender distribution.The following two, DIP and RB-ILD, are at extremes of a spectrum, are associated with smoking, and have good response with smoking cessation.One caveat: The word chronic in the mnemonic should be taken with a grain of salt. Some of the entities may have a subacute presentation, and one, AIP, presents acutely.