Intra-articular loose bodies
Updates to Article Attributes
Intra articular loose bodies can result from a variety of pathological processes.
Use of the term loose is frowned upon by some because the fragments do not necessarily rattle around in the joint : the term intraarticular fragment is a safer alternative.
Patients may be entirely asymptomatic, or complain of pain, clicking and locking, depending on the location and mobility of the fragment as well as any associated secondary degenerative disease, and symptoms from the underlying cause.
Causes include
- osteochondral fractures
- osteochondritis dissecans
- pigmented villonodular synovitis (PVNS)
- osteoarthritis
- intra-articular fracture fragments
- synovial osteochondromatosis
- neuropathic joints
- meniscal fragmentation and its calcification
Pathogenesis
Intra-articular bodies are composed of cartilage or cartilage and bone and result form any process that leads to disruption of the articular surface. They derive nutrition from synovial fluid and contain any of the cells of bone or cartilage. The surface cells form more cartilaginous layers, so enlarging the body over time. Deeper cells receive less nutrition resulting in cell death and calcification 2.
-<p><strong>Intra articular loose bodies</strong> can result from a variety of pathological processes.</p><p>Use of the term <em>loose</em> is frowned upon by some because the fragments do not necessarily rattle around in the joint : the term <em>intraarticular fragment</em> is a safer alternative.-</p><p>Patients may be entirely asymptomatic, or complain of pain, clicking and locking, depending on the location and mobility of the fragment as well as any associated secondary degenerative disease, and symptoms from the underlying cause.-</p><h6>Causes include </h6><ul>-<li><a href="/articles/osteochondral-fracture">osteochondral fractures</a></li>-<li><a href="/articles/osteochondritis_dissecans">osteochondritis dissecans</a></li>-<li><a href="/articles/pvns">pigmented villonodular synovitis (PVNS)</a></li>-<li><a href="/articles/osteoarthritis">osteoarthritis</a></li>-<li>intra-articular fracture fragments</li>-<li><a href="/articles/primary-synovial-chondromatosis" title="Synovial osteochondromatosis">synovial osteochondromatosis</a></li>-<li><a href="/articles/neuropathic-joints">neuropathic joints</a></li>-<li>meniscal fragmentation and its calcification</li>-</ul>- +<p><strong>Intra articular loose bodies</strong> can result from a variety of pathological processes.</p><p>Use of the term <em>loose</em> is frowned upon by some because the fragments do not necessarily rattle around in the joint : the term <em>intraarticular fragment</em> is a safer alternative.</p><p>Patients may be entirely asymptomatic, or complain of pain, clicking and locking, depending on the location and mobility of the fragment as well as any associated secondary degenerative disease, and symptoms from the underlying cause.</p><h6>Causes include </h6><ul>
- +<li><a href="/articles/osteochondral-fracture">osteochondral fractures</a></li>
- +<li><a href="/articles/osteochondritis-dissecans">osteochondritis dissecans</a></li>
- +<li><a href="/articles/pvns">pigmented villonodular synovitis (PVNS)</a></li>
- +<li><a href="/articles/osteoarthritis">osteoarthritis</a></li>
- +<li>intra-articular fracture fragments</li>
- +<li><a href="/articles/primary-synovial-chondromatosis">synovial osteochondromatosis</a></li>
- +<li><a href="/articles/neuropathic-joints">neuropathic joints</a></li>
- +<li>meniscal fragmentation and its calcification</li>
- +</ul><h6>Pathogenesis</h6><p>Intra-articular bodies are composed of cartilage or cartilage and bone and result form any process that leads to disruption of the articular surface. They derive nutrition from synovial fluid and contain any of the cells of bone or cartilage. The surface cells form more cartilaginous layers, so enlarging the body over time. Deeper cells receive less nutrition resulting in cell death and calcification <sup>2.</sup></p>
References changed:
- 2. Milgram J, Gilden J, Gilula L. Multiple Loose Bodies: Formation, Revascularization, and Resorption. A 29-Year Followup Study. Clin Orthop Relat Res. 1996;(322):152-7. - <a href="https://www.ncbi.nlm.nih.gov/pubmed/8542691">Pubmed</a>
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