Intradiploic epidermoid cyst

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Intradiploic epidermoid cysts represent epidermoid cysts that occur in the diploe of the skull.

Clinical presentation

Painless slowly progressive scalp swelling.

Pathology

epidermoid cysts may be congenital (most common, arising from ectodermal inclusion during neural tube closure and subsequently remain within the cranial bones) or acquired (e.g. post-surgical or post-traumatic implantation) ⁴
intradiploic epidermoids are less frequent than the intradural variety ¹

Radiographic features

Intradiploic epidermoids occurs within the frontal, parietal, occipital, sphenoid bones as well as the spine ¹.

Plain radiograph

rounded or lobulated area of bone destruction, well-delineated sclerotic scalloped margins

CT

non-enhancing hypodense lesion with sharply demarcated bony defects and zones of calcifications
it may alter the outer or inner tables of the skull (the inner table more than the outer)

MRI

T1: slightly hyperintense to the CSF
T2: isointense/hyperintense to the CSF
FLAIR: hyperintense to the CSF space
DWI: restricted diffusion with characteristic hyperintensity
T1C+: none

History and etymology

The first IEC was reported by Müller J in 1838⁵.

The radiological pattern of intradiploic epidermoids was first described by Cushing in 1922.

Differential diagnosis

Consider:

eosinophilic granuloma
haemangioma
dermoid cyst
fibrous dysplasia

-</ul><h4>History and etymology</h4><p>The radiological pattern of intradiploic epidermoids was first described by <strong>Cushing</strong> in 1922.</p><h4>Differential diagnosis</h4><p>Consider:</p><ul>
+</ul><h4>History and etymology</h4><p>The first IEC was reported by Müller J in 1838<sup>5</sup>.</p><p>The radiological pattern of intradiploic epidermoids was first described by <strong>Cushing</strong> in 1922.</p><h4>Differential diagnosis</h4><p>Consider:</p><ul>

References changed:

5. Müller J. Über den feineren Bau und die Formen der krankhaftenGeschwfilste. Berlin, Germany: G. Reimer; 1838.

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