Intradiploic epidermoid cyst

Changed by Yuranga Weerakkody, 21 Jul 2022
Disclosures - updated 10 May 2022: Nothing to disclose

Updates to Article Attributes

Body was changed:

Intradiploic epidermoid cysts refer to epidermoid cysts that occur in the diploë of the skull.

Clinical presentation

Painless slowly progressive scalp swelling.

Pathology

  • epidermoid cysts may be congenital (most common, arising from ectodermal inclusion during neural tube closure and subsequently remain within the cranial bones) or acquired (e.g. post-surgical or post-traumatic implantation) 4
  • intradiploic epidermoids are less frequent than the intradural variety 1

Radiographic features

Intradiploic epidermoids occurs within the frontal, parietal, occipital and sphenoid bones, as well as the spine 1.

Plain radiograph
  • rounded or lobulated area of bone destruction, well-delineated sclerotic scalloped margins
CT
  • non-enhancing hypodense lesion with sharply demarcated bony defects and zones of calcifications
  • it may alter the outer and/or inner tables of the skull (the inner table more than the outer)
MRI
  • T1: slightly hyperintense to the CSF
  • T2: isointense/hyperintense to the CSF
  • FLAIR: hyperintense to the CSF space
  • DWI: restricted diffusion with characteristic hyperintensity
  • T1C+: none

History and etymology

The first intradiploic epidermoid cyst was reported by J Müller in 1838 5.

The radiological pattern of intradiploic epidermoids was first described by Cushing in 1922.

Differential diagnosis

Consider:

  • -<li><a title="Dermoid cyst of the anterior fontanelle" href="/articles/anterior-fontanelle-inclusion-cyst">dermoid cyst</a></li>
  • +<li><a href="/articles/anterior-fontanelle-inclusion-cyst">dermoid cyst</a></li>
Images Changes:

Image 9 MRI (FLAIR) ( create )

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