Juxtapleural lung nodules

Changed by Arjun Shivananda, 8 Oct 2018

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Perifissural lung nodules (PFNs) are a type of intrapulmonary nodules that, most of the times, represent pulmonary lymph nodes

Terminology 

Although perilymphatic pulmonary nodules can also be perifissural in distribution, they should be distinguished from PFNs, as they are usually associated with a number of conditions. 

Radiographic features

CT

PFNs are typically seen as well-circumscribed, smoothly marginated homogeneous nodules in contact with or closely related to a pulmonary fissure. Most show a triangular, oval/lentiform, rectangular, or dumbbell shape. They may often show a septal attachment to the pleural surface 3.

Worrisome features that are not typical for lymph nodes and should be reported, prompting for imaging follow-up, include 6

  • round morphology or contour irregularity
  • the adjacent fissure is abnormal: bowed, retracted, or transgressed

Treatment and prognosis

If they have typical morphology they are favoured to be benign despite some nodules having a tendency to grow over serial scans 2.

  • -<p><strong>Perifissural lung nodules (PFNs)</strong> are a type of <a href="/articles/intrapulmonary-nodules">intrapulmonary nodules</a> that, most of the times, represent <a href="/articles/intrapulmonary-lymph-nodes-1">pulmonary lymph nodes</a>. </p><h4>Terminology </h4><p>Although <a href="/articles/perilymphatic-lung-nodules">perilymphatic pulmonary nodules</a> can also be perifissural in distribution, they should be distinguished from PFNs, as they are usually associated with a number of conditions. </p><h4>Radiographic features</h4><h5>CT</h5><p>PFNs are typically seen as well-circumscribed, smoothly marginated nodules in contact with or closely related to a pulmonary fissure. Most show a triangular, oval/lentiform, rectangular, or dumbbell shape. They may often show a septal attachment to the pleural surface <sup>3</sup>.</p><p>Worrisome features that are not typical for lymph nodes and should be reported, prompting for imaging follow-up, include <sup>6</sup>: </p><ul>
  • +<p><strong>Perifissural lung nodules (PFNs)</strong> are a type of <a href="/articles/intrapulmonary-nodules">intrapulmonary nodules</a> that, most of the times, represent <a href="/articles/intrapulmonary-lymph-nodes-1">pulmonary lymph nodes</a>. </p><h4>Terminology </h4><p>Although <a href="/articles/perilymphatic-lung-nodules">perilymphatic pulmonary nodules</a> can also be perifissural in distribution, they should be distinguished from PFNs, as they are usually associated with a number of conditions. </p><h4>Radiographic features</h4><h5>CT</h5><p>PFNs are typically seen as well-circumscribed, smoothly marginated homogeneous nodules in contact with or closely related to a pulmonary fissure. Most show a triangular, oval/lentiform, rectangular, or dumbbell shape. They may often show a septal attachment to the pleural surface <sup>3</sup>.</p><p>Worrisome features that are not typical for lymph nodes and should be reported, prompting for imaging follow-up, include <sup>6</sup>: </p><ul>

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