Lipomatous metaplasia of the myocardium

Lipomatous metaplasia of the myocardium is a phenomenon where there is fat deposition within the myocardium. It is often seen following a myocardial infarction but can also rarely been seen in conditions such as arrhythmogenic right ventricular dysplasia.


The exact etiology of lipomatous metaplasia is not known, but it is not seen in the absence of substitutive myocardial fibrosis.

Radiographic features


Lipomatous hyperplasia may not be detectable on echocardiography 4.


Lipomatous hyperplasia may not be detectable on myocardial perfusion imaging as lipophilic myocardial perfusion agents such as tetrofosmin and sestamibi may well be taken up into fat cells 4

Cardiac CT

May show areas of fat attenuation within the affected myocardial region.

Cardiac MRI
  • T1: affected regions are high signal and show signal dropout in fat suppressed sequences. 
  • IR (inversion recovery): the adipose tissue has high signal intensity
  • C+ (Gd): may not enhance but affected areas are seen surrounded by areas of myocardial fibrosis demonstrated on late contrast‐enhanced (LCE) images 1.
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Article information

rID: 24929
System: Cardiac
Tag: cases
Synonyms or Alternate Spellings:
  • Lipomatous metaplasia (LM) of myocardium
  • Myocardial lipomatous metaplasia
  • Myocardial fat replacement
  • Lipomatous metaplasia of myocardium

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