Löffler syndrome
Updates to Article Attributes
Simple pulmonary eosinophilia (also known as Löffler syndrome) is a type of pulmonary eosinophilia that typically typically presents with transient radiographic infiltrates, minimal constitutional upset and an elevated eosinophil count in peripheral blood.
Pathology
Causes
Usually the cause is not identified but a number of allergens have been linked to the syndrome.
- parasites (ascaris, strongyloides, ankylostoma)
- drugs (aspirin, penicillin)
Radiographic features
Plain film - chest radiograph / HRCTCT
There is often a fleeting type transient non segmental air space opacification which may be unilateral or bilateral. Usually has predominantly peripheral distribution. Pleural effusions and lymphadenopathy is not a feature.
Complications
A restrictive type cardiomyopathy can develop from endomyocardial fibrosis.
Treatment and prognosis
The condition is usually self-limiting and treated conservatively. OpacitiesOpacities typically resolve within a month 3,5.
Complications
A restrictive type cardiomyopathy can develop from endomyocardial fibrosis.
History and etymology
Named afterWilhelm Löffler - Swiss, Swiss physician (1887-1972), who first described the case histories of patients with chest radiographic infiltrates in 1932.
Differential diagnosis
General imaging differential considerations include
- recurrent aspiration
- pulmonary haemorrhage
- pulmonary vasculitis
- cryptogenic organising pneumonia (COP)
-<p><strong>Simple pulmonary eosinophilia</strong> (also known as <strong>Löffler syndrome</strong>) is a type of <a href="/articles/eosinophilic_pneumonia">pulmonary eosinophilia</a> that typically presents with transient radiographic infiltrates, minimal constitutional upset and an elevated eosinophil count in peripheral blood.</p><h4>Pathology</h4><h5>Causes</h5><p>Usually the cause is not identified but a number of allergens have been linked to the syndrome.</p><ul>- +<p><strong>Simple pulmonary eosinophilia</strong> (also known as <strong>Löffler syndrome</strong>) is a type of <a href="/articles/eosinophilic_pneumonia">pulmonary eosinophilia</a> that typically presents with transient radiographic infiltrates, minimal constitutional upset and an elevated eosinophil count in peripheral blood.</p><h4>Pathology</h4><h5>Causes</h5><p>Usually the cause is not identified but a number of allergens have been linked to the syndrome.</p><ul>
-</ul><h4>Radiographic features </h4><h5>Plain film - chest radiograph / HRCT</h5><p>There is often a fleeting type transient non segmental air space opacification which may be unilateral or bilateral. Usually has predominantly peripheral distribution. Pleural effusions and lymphadenopathy is not a feature.</p><h5>Complications</h5><p>A restrictive type cardiomyopathy can develop from <a href="/articles/endomyocardial-fibrosis">endomyocardial fibrosis</a>.</p><h4>Treatment and prognosis </h4><p>The condition is usually self-limiting and treated conservatively. Opacities typically resolve within a month <sup>3,5</sup>.</p><h4>History and etymology </h4><p>Named after <strong>Wilhelm Löffler</strong> - Swiss physician (1887-1972) who first described the case histories of patients with chest radiographic infiltrates in 1932.</p><h4>Differential diagnosis</h4><p>General imaging differential considerations include</p><ul>- +</ul><h4>Radiographic features </h4><h5>Plain radiograph / CT</h5><p>There is often a fleeting type transient non segmental air space opacification which may be unilateral or bilateral. Usually has predominantly peripheral distribution. Pleural effusions and lymphadenopathy is not a feature.</p><h4>Treatment and prognosis </h4><p>The condition is usually self-limiting and treated conservatively. Opacities typically resolve within a month <sup>3,5</sup>.</p><h5>Complications</h5><p>A restrictive type cardiomyopathy can develop from <a href="/articles/endomyocardial-fibrosis">endomyocardial fibrosis</a>.</p><h4>History and etymology </h4><p>Named after <strong>Wilhelm Löffler</strong>, Swiss physician (1887-1972), who first described the case histories of patients with chest radiographic infiltrates in 1932.</p><h4>Differential diagnosis</h4><p>General imaging differential considerations include</p><ul>
-<li><a href="/articles/pulmonary-haemorrhage">pulmonary haemorrhage </a></li>- +<li><a href="/articles/pulmonary-haemorrhage">pulmonary haemorrhage </a></li>
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