Loss of corticomedullary differentiation

Last revised by Yuranga Weerakkody on 11 Jan 2024

A loss of corticomedullary differentiation is an imaging feature where renal cortex and medulla is no longer able to be seen as different structures.

Pathology

It can be detected usually by ultrasound or MRI (and in some instances on contrast CT) with a large number of variable pathological conditions.

Such examples are not confined to but include

It can be observed in either an acute or chronic setting and this feature on its own may not be reliable in differentiating chronicity 2. It may be localized to a portion of the kidney or maybe be diffusely observed throughout the kidneys.

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