Medial medullary syndrome
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Medial medullary syndrome, also known as DejerineDéjerine syndrome, represents less than 1% of brainstem stroke syndromes 1,2. Thrombotic or embolic occlusion of small perforating branches from vertebral or proximal basilar artery supplying the medial aspect of medulla oblongata cause this rare syndrome 1,2. It is characterized by contralateral hemiplegia/hemiparesis as well as hemisensory loss with ipsilateral hypoglossal palsy (ipsilateral tongue weakness and atrophy) from involvement of CN XII nucleus 1,2. Other manifestations such as vertigo, nausea, or contralateral limb ataxia are also reported 1,2.
History and etymology
The syndrome was first described by Joseph DejerineJules Déjerine (1849-1917), a French physicianneurologist, in 1915 3.
-<p><strong>Medial medullary syndrome</strong>, also known as <strong>Dejerine syndrome</strong>, represents less than 1% of <a href="/articles/brainstem-stroke-syndromes">brainstem stroke syndromes</a> <sup>1,2</sup>. Thrombotic or embolic occlusion of small perforating branches from vertebral or proximal basilar artery supplying the medial aspect of <a href="/articles/medulla-oblongata">medulla oblongata</a> cause this rare syndrome <sup>1,2</sup>. It is characterized by contralateral hemiplegia/hemiparesis as well as hemisensory loss with ipsilateral hypoglossal palsy (ipsilateral tongue weakness and atrophy) from involvement of <a href="/articles/hypoglossal-nerve">CN XII</a> nucleus <sup>1,2</sup>. Other manifestations such as vertigo, nausea, or contralateral limb ataxia are also reported <sup>1,2</sup>.</p><h4>History and etymology</h4><p>The syndrome was first described by <strong>Joseph Dejerine</strong> (1849-1917), a French physician, in 1915 <sup>3</sup>.</p>- +<p><strong>Medial medullary syndrome</strong>, also known as <strong>Dé</strong><strong>jerine syndrome</strong>, represents less than 1% of <a href="/articles/brainstem-stroke-syndromes">brainstem stroke syndromes</a> <sup>1,2</sup>. Thrombotic or embolic occlusion of small perforating branches from vertebral or proximal basilar artery supplying the medial aspect of <a href="/articles/medulla-oblongata">medulla oblongata</a> cause this rare syndrome <sup>1,2</sup>. It is characterized by contralateral hemiplegia/hemiparesis as well as hemisensory loss with ipsilateral hypoglossal palsy (ipsilateral tongue weakness and atrophy) from involvement of <a href="/articles/hypoglossal-nerve">CN XII</a> nucleus <sup>1,2</sup>. Other manifestations such as vertigo, nausea, or contralateral limb ataxia are also reported <sup>1,2</sup>.</p><h4>History and etymology</h4><p>The syndrome was first described by <strong>Joseph Jules Dé</strong><strong>jerine </strong>(1849-1917), a French neurologist, in 1915 <sup>3</sup>.</p>
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