Melanocytic lesions of the central nervous system
Updates to Article Attributes
Body
was changed:
A number of pathological entities affecting the central nervous system contain melanin. They can be divided into primary and secondary melanocytic lesions.
Primary
Primary melanocytic lesions arise from melanin-containing neural crest cells which are located in the leptomeninges. They include 1-3:
-
meningeal melanomatosis - melanocytoma
- primary meningeal malignant melanoma
of the CNS
In addition to these primary lesions which arise from melanin-containing cells, a number of other tumours of the CNS can rarely contain melanin. These include 3:
- melanotic meningioma
- melanotic schwannoma
- melanotic medulloblastoma
- melanotic differentiation of low-grade gliomas
- craniopharyngiomas may rarely contain melanin
- melanotic differentiation of a gliosarcoma (single case report 4)
Secondary
Secondary melanocytic lesions are far more common and represent metastatic malignant melanoma.
-<li>-<a href="/articles/neurocutaneous-melanosis">meningeal melanomatosis</a> (seen in <a href="/articles/neurocutaneous-melanosis">neurocutaneous melanosis</a>)</li>- +<li>diffuse melanosis (seen in <a href="/articles/neurocutaneous-melanosis">neurocutaneous melanosis</a>)<ul>
- +<li><a href="/articles/meningeal-melanocytosis">meningeal melanocytosis</a></li>
- +<li><a href="/articles/neurocutaneous-melanosis">meningeal melanomatosis</a></li>
- +</ul>
- +</li>
-<li>-<a href="/articles/primary-malignant-melanoma-of-the-cns">primary malignant melanoma of the CNS</a> </li>- +<li><a title="Primary meningeal malignant melanoma" href="/articles/primary-meningeal-malignant-melanoma">primary meningeal malignant melanoma</a></li>
- +<li><a href="/articles/melanotic-meningioma">melanotic meningioma</a></li>
Unable to process the form. Check for errors and try again.