As a general rule any mucin-producing tumor will produce very high T2 signal 1.
An enhancing lesion, irregular margin, and isointensity on T1 are features that would weigh towards a malignant lesion rather than a benign one 2.
For more well-defined high T2 signal lesions on MRI, consider
- atypical nabothian cyst: tends to have high signal on T1 and no enhancement post contrast
- adenoma malignum: considered a type of mucinous carcinoma of the cervix
- WHO histological classification of tumors of the uterine cervix
- 1. Hussain SM, Outwater EK, Siegelman ES. MR imaging features of pelvic mucinous carcinomas. Eur Radiol. 2000;10 (6): 885-91. Eur Radiol (link) - Pubmed citation
- 2. Li H, Sugimura K, Okizuka H et-al. Markedly high signal intensity lesions in the uterine cervix on T2-weighted imaging: differentiation between mucin-producing carcinomas and nabothian cysts. Radiat Med. 17 (2): 137-43. - Pubmed citation
- 3. Okamoto Y, Tanaka YO, Nishida M et-al. MR imaging of the uterine cervix: imaging-pathologic correlation. Radiographics. 23 (2): 425-45. doi:10.1148/rg.232025065 - Pubmed citation