Neuroblastoma vs Wilms tumor
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Both neuroblastoma and Wilms tumour occur in early childhood and typically present as large abdominal masses closely related to the kidneys. Distinguishing between the two is important, and a number of features are helpful.
Neuroblastoma
- calcification very common: 90%
- encases vascular structures but does not invade them
- younger age group (<2 years of age)
- poorly marginated
- elevates the aorta away from the vertebral column
- more commonly crosses the midline, especially behind the aorta 2
- more common to have extension into the chest
- Bony metastasis are common (Hutchinson syndrome)
- Extension into spinal canal can be seen.
- Retroperitoneal lymph nodes are more often seen.
Wilms tumour
- calcification uncommon: 10-15% (10% rule of Wilm's tumour)
- displaces adjacent structures without insinuating between them
- slightly older age group: peak 3-4 years of age
- well circumscribed
- claw sign with the kidney
- extension into IVC/renal vein.
- Bony metastasis are rare, rather lung metastasis are common.
- Extension into spinal canal never seen.
- Retroperitoneal lymphadenopathy is uncommon.
- +<li>Bony metastasis are common (Hutchinson syndrome)</li>
- +<li>Extension into spinal canal can be seen.</li>
- +<li>Retroperitoneal lymph nodes are more often seen.</li>
-<li>calcification uncommon: 10-15%</li>- +<li>calcification uncommon: 10-15% (10% rule of Wilm's tumour)</li>
-<li>extension into IVC/renal vein</li>- +<li>extension into IVC/renal vein.</li>
- +<li>Bony metastasis are rare, rather lung metastasis are common.</li>
- +<li>Extension into spinal canal never seen.</li>
- +<li>Retroperitoneal lymphadenopathy is uncommon.</li>
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