Non-bacterial thrombotic endocarditis
Updates to Synonym Attributes
Updates to Article Attributes
Nonbacterial thrombotic endocarditis (NBTE), also referred as marantic endocarditis, correspondsrefers to fibrin and platelets aggregations on previously undamaged heart valves, in patients without bloodstream bacterial infectionbacteraemia. The condition is seen in patients with advanced stage malignancies, and is related to episodes of multisystemic emboli.
Epidemiology
NBTE is usually present in patients ranging between the 4th and the 8th decades of life, however, the real incidence is unknown 1-2. A higher incidence has been reported among patients with advanced stage malignancies, connective tissue disorders, autoimmune disorders (e.g. systemic lupus erythematosus), and hypercoagulable states 1-3.
Clinical presentation
The condition has no specific clinicclinical signs or symptoms. Presence of a new heart murmur on clinical examination has been reported, but definitely is signs. Signs of multiple systemic emboli without a known source or an infectious process that will raise the possibility of this diagnosis.
-<p><strong>Nonbacterial thrombotic endocarditis (NBTE)</strong>, also referred as <strong>marantic endocarditis</strong>, corresponds to fibrin and platelets aggregations on previously undamaged heart valves, in patients without bloodstream bacterial infection. The condition is seen in patients with advanced stage malignancies and is related to episodes of multisystemic emboli. </p><h4>Epidemiology</h4><p>NBTE is usually present in patients ranging between the 4th and the 8th decades of life, however, the real incidence is unknown <sup>1-2</sup>. A higher incidence has been reported among patients with advanced stage malignancies, connective tissue disorders, autoimmune disorders (e.g. systemic lupus), and hypercoagulable states <sup>1-3</sup>. </p><h4>Clinical presentation</h4><p>The condition has no specific clinic signs or symptoms. Presence of a new heart murmur on clinical examination has been reported, but definitely is signs of multiple systemic emboli without a known source or an infectious process that will raise the possibility of this diagnosis. </p>- +<p><strong>Nonbacterial thrombotic endocarditis (NBTE)</strong>, also referred as <strong>marantic endocarditis</strong>, refers to fibrin and platelets aggregations on previously undamaged heart valves, in patients without bacteraemia. The condition is seen in patients with advanced stage malignancies, and is related to episodes of multisystemic emboli. </p><h4>Epidemiology</h4><p>NBTE is usually present in patients ranging between the 4th and the 8th decades of life, however, the real incidence is unknown <sup>1-2</sup>. A higher incidence has been reported among patients with advanced stage malignancies, connective tissue disorders, autoimmune disorders (e.g. <a title="Systemic lupus erythematosus" href="/articles/systemic-lupus-erythematosus">systemic lupus erythematosus</a>), and hypercoagulable states <sup>1-3</sup>. </p><h4>Clinical presentation</h4><p>The condition has no specific clinical signs or symptoms. Presence of a new heart murmur on clinical examination has been reported. Signs of multiple systemic emboli without a known source or an infectious process will raise the possibility of this diagnosis. </p>
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