Olfactory nerve

Changed by Craig Hacking, 2 Jun 2016

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The olfactory nerve (CN I) is the first and most rostral of the cranial nerves. Along with the optic nerve, it is actually a peripheral outpost of the central nervous system.

The bipolar cell is the first first-order sensory neuron located located in the roof of the nose, immediately inferior to the cribriform plate of the ethmoid bone. This cell is analogous to the sensory cells of spinal nerves, whose cell bodies reside in the dorsal root ganglion. Their central processes form filaments (approximately 20) which pass through the cribriform plate, pierce the dura mater and relay in the olfactory bulb. The central process of these second-order neurons forms the olfactory nerve which passes posteriorly within the the olfactory grooves of the anterior cranial fossa and then in-between the gyrus rectus medially and medial orbital gyrus medially.

Anterior to the anterior anterior perforated substance, they form medial and lateral olfactory striae. The lateral olfactory striae project to the to the uncus. The medial olfactory striae ultimately ultimately project to to the hypothalamus and brainstem nuclei. 

Coronal images are the best to depict theolfactory nerve as it is situated deep in the olfactory groove.

  • -<p>The <strong>olfactory nerve (CN I)</strong> is the first and most rostral of the <a href="/articles/cranial-nerves">cranial nerves</a>. Along with the <a href="/articles/optic-nerve">optic nerve</a>, it is actually a peripheral outpost of the central nervous system.</p><p>The bipolar cell is the first-order sensory neuron located in the roof of the nose, immediately inferior to the <a href="/articles/cribriform-plate">cribriform plate</a> of the <a href="/articles/ethmoid-bone">ethmoid bone</a>. This cell is analogous to the sensory cells of spinal nerves, whose cell bodies reside in the <a href="/articles/dorsal-root-ganglion">dorsal root ganglion</a>. Their central processes form filaments (approximately 20) which pass through the cribriform plate, pierce the <a href="/articles/dura-mater">dura mater</a> and relay in the <a href="/articles/olfactory-bulb">olfactory bulb</a>. The central process of these second-order neurons forms the <a href="/articles/olfactory-nerve">olfactory nerve</a> which passes posteriorly within the <a href="/articles/olfactory-groove">olfactory grooves</a> of the <a href="/articles/anterior-cranial-fossa">anterior cranial fossa</a> and then in-between the <a title="Gyrus rectus" href="/articles/gyrus-rectus">gyrus rectus</a> medially and <a title="medial orbital gyrus" href="/articles/medial-orbital-gyrus">medial orbital gyrus</a> medially.</p><p>Anterior to the anterior perforated substance, they form medial and lateral olfactory striae. The lateral olfactory striae project to the uncus. The medial olfactory striae ultimately project to the hypothalamus and brainstem nuclei. </p><p>Coronal images are the best to depict the <a href="/articles/olfactory-nerve">olfactory nerve</a> as it is situated deep in the olfactory groove.</p>
  • +<p>The <strong>olfactory nerve (CN I)</strong> is the first and most rostral of the <a href="/articles/cranial-nerves">cranial nerves</a>. Along with the <a href="/articles/optic-nerve">optic nerve</a>, it is actually a peripheral outpost of the central nervous system.</p><p>The bipolar cell is the first-order sensory neuron located in the roof of the nose, immediately inferior to the <a href="/articles/cribriform-plate">cribriform plate</a> of the <a title="Ethmoid bone" href="/articles/ethmoid-bone-1">ethmoid bone</a>. This cell is analogous to the sensory cells of spinal nerves, whose cell bodies reside in the <a href="/articles/dorsal-root-ganglion">dorsal root ganglion</a>. Their central processes form filaments (approximately 20) which pass through the cribriform plate, pierce the <a href="/articles/dura-mater">dura mater</a> and relay in the <a title="olfactory bulb" href="/articles/olfactory-bulb">olfactory bulb</a>. The central process of these second-order neurons forms the <a href="/articles/olfactory-nerve">olfactory nerve</a> which passes posteriorly within the <a href="/articles/olfactory-groove">olfactory grooves</a> of the <a href="/articles/anterior-cranial-fossa">anterior cranial fossa</a> and then in-between the <a href="/articles/gyrus-rectus">gyrus rectus</a> medially and <a href="/articles/medial-orbital-gyrus">medial orbital gyrus</a> medially.</p><p>Anterior to the anterior perforated substance, they form medial and lateral olfactory striae. The lateral olfactory striae project to the <a title="Uncus" href="/articles/uncus">uncus</a>. The medial olfactory striae ultimately project to the <a title="Hypothalamus" href="/articles/hypothalamus">hypothalamus</a> and brainstem nuclei. </p><p>Coronal images are the best to depict the <a href="/articles/olfactory-nerve">olfactory nerve</a> as it is situated deep in the olfactory groove.</p>

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