Organizing pneumonia
Updates to Article Attributes
Organising pneumonia (OP) refers to a clinicopathological entity which is associated with non-specific clinical findings, radiographic findings, and pulmonary function test results.
When an underlying cause is unknown it is classified as cryptogenic organising pneumonia (COP; also referred to as primary organising pneumonia) whereas if a cause is known it is then termed a secondary organising pneumonia.
Epidemiology
Most cases of OP (50-70%) are classified as cryptogenic 5,6.
Pathology
Microscopic appearance
OP comprises a histological pattern characterised by granulation tissue polyps within alveolar ducts and alveoli and with chronic inflammation involving the adjacent lung parenchyma.
Treatment and prognosis
Most (especially cryptogenic forms) respond very well to corticosteroid treatment; however, a small percentage of patients many develop progressive fibrosis - fibrosing organising pneumonia7.
-<p><strong>Organising pneumonia (OP)</strong> refers to a clinicopathological entity which is associated with non-specific clinical findings, radiographic findings, and pulmonary function test results.</p><p>When an underlying cause is unknown it is classified as <a href="/articles/cryptogenic-organising-pneumonia-1">cryptogenic organising pneumonia</a> (<strong>COP</strong>; also referred to as <strong>primary organising pneumonia</strong>) whereas if a cause is known it is then termed a <a href="/articles/secondary-organising-pneumonia">secondary organising pneumonia</a>. </p><h4>Epidemiology</h4><p>Most cases of OP (50-70%) are classified as cryptogenic <sup>5,6</sup>.</p><h4>Pathology</h4><h5>Microscopic appearance</h5><p>OP comprises a histological pattern characterised by granulation tissue polyps within alveolar ducts and alveoli and with chronic inflammation involving the adjacent lung parenchyma. </p><h4>Treatment and prognosis</h4><p>Most (especially cryptogenic forms) respond very well to corticosteroid treatment; however, a small percentage of patients many develop progressive fibrosis<sup> 7</sup>.</p>- +<p><strong>Organising pneumonia (OP)</strong> refers to a clinicopathological entity which is associated with non-specific clinical findings, radiographic findings, and pulmonary function test results.</p><p>When an underlying cause is unknown it is classified as <a href="/articles/cryptogenic-organising-pneumonia-1">cryptogenic organising pneumonia</a> (<strong>COP</strong>; also referred to as <strong>primary organising pneumonia</strong>) whereas if a cause is known it is then termed a <a href="/articles/secondary-organising-pneumonia">secondary organising pneumonia</a>. </p><h4>Epidemiology</h4><p>Most cases of OP (50-70%) are classified as cryptogenic <sup>5,6</sup>.</p><h4>Pathology</h4><h5>Microscopic appearance</h5><p>OP comprises a histological pattern characterised by granulation tissue polyps within alveolar ducts and alveoli and with chronic inflammation involving the adjacent lung parenchyma. </p><h4>Treatment and prognosis</h4><p>Most (especially cryptogenic forms) respond very well to corticosteroid treatment; however, a small percentage of patients many develop progressive fibrosis - <a title="fibrosing organising pneumonia" href="/articles/fibrosing-organising-pneumonia">fibrosing organising pneumonia</a> <sup>7</sup>.</p>
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